Purpose: This study aimed to examine the effects of single-task, dual-task and successive physical-cognitive training on fall risk, balance, and gait performances in elderly.Methods: A total of 45 healthy older adults (73.0±4.6 years; 6 male and 39 female) underwent one of three interventions 3 times a week for 4 weeks. Group-1 performed single-task balance and gait exercises. Group-2 performed cognitive activity, balance, and gait exercises simultaneously. Group-3 performed successive cognitive activities and balance and gait exercises. Gait speed under single-task and dual-task conditions, Berg Balance Scale, Timed up and Go test, and Tinetti's Falls Efficacy Scale scores were evaluated before and after 4 weeks of interventions.Results: Gait speed under single-task condition, Timed up and Go Test, and Berg Balance Scale scores were improved in all groups (p<0.05). Gait speed under dual-task condition was improved in Groups-2 and 3 (p<0.05). Group-3 had greater improvement in Berg Balance Scale and Timed up and Go test scores than Group-2. Tinetti's Falls Efficacy Scale was improved in Group-1 and 3 after training while the improvement was greater in Group-3 (p=0.001).Conclusion: The present study suggests that an intervention involving cognitive and physical activities results in greater improvement in gait speed than interventions involving physical activities alone. However, successive physical-cognitive training may be more effective in reducing fear of fall and improving balance skills in elderly.
Temporal lob epilepsisi ve Alzheimer hastalığı (AH), hipokampus ve meziyal temporal yapılarda benzer bir fizyopatoloji sergiler. Her iki hastalıkta da klinik bulgulardan önce nöral ağ değişiklikleri mevcuttur. İki antite arasındaki bu benzerlik nedeniyle, çeşitli çalışmalarda nöbetler ve bunama arasında nasıl bir ilişki olduğu araştırılmıştır. Bu çalışmada ise, meziyal temporal sklerozlu bireylerin demansa daha yatkın olup olmadığı ve AH’nin epilepsiye yol açıp açmadığı sorularına cevap aranmıştır. Bu doğrultuda, biri uzun yıllardır epilepsi tedavisi görmekteyken demans tanısı alan, diğerine ise aynı anda hem epilepsi hem demans tanısı konan yetmişli yaşlardaki iki hastanın klinik bulguları ele alınmıştır. Diğer bir konu olarak da, AH’de nöbet görülme olasılığının oldukça yüksek olmasından doğan AH’nin nöbetlere yol açıp açmadığı sorusu ve bunun kognitif yıkımla olan ilişkisi, çeşitli çalışmalardan veriler ışığında tartışılmıştır. Ayrıca bu ilişki hızlanmış unutma ve konsolidasyon bağlamında da ele alınmıştır.
Aim: To investigate the clinical characteristics and cerebral FDG PET metabolisms of dementia patients who also diagnosed with epilepsy and compare the differences between with the pure Alzheimer dementia patients. Methods: In this case-control study, a total of 14 patients; 7 patients with pure Alzheimer disease as a control group and 7 age and gender matched patients with Alzheimer disease and concomitant epilepsy as a study group were included. Detailed neurocognitive battery and brain fludeoxyglucose positron emission tomography (FDG PET-CT) were performed for all subjects. Results: In comparison of neurocognitive test scores, there was no significant difference between study and control groups. However, geriatric depression scale scores were significantly lower in study group than the controls (p= 0.026). In cerebral FDG-PET CT profiles of subjects we detected significantly lower metabolism in left and right cerebellum, left lentiform nucleus, right thalamus and vermis in the study group (p=0.008, p=0.023, p=0.003, p=0.002, p=0.002, respectively). In the right parietotemporal cortex and right and left associative visual cortex, we found higher metabolism in the study group than controls ( p=0.023, p=0.012, p=0.003, respectively). Conclusion: Epileptic patients with Alzheimer dementia may have distinct clinical and metabolic profile than pure Alzheimer disease patients. Even if there is no difference in the neurocognitive clinical scores of the patients, depression and related functional abnormalities may be a biomarker of epileptic AD.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.