Isoflavans have gained considerable interest owing to their potential health benefits. Herein, we have presented a straightforward strategy for isoflavans synthesis. The strategy features an intermolecular [Cu]‐catalyzed arylation of malonates and an intramolecular [Pd]‐catalyzed Buchwald coupling of hydroxy tethered bromoarenes as the key transformations. This protocol enabled the synthesis of a variety of isoflavan analogs.
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