In order to follow the Preventive Chemotherapy (PC) for the transmission control as recommended by WHO, Gabon initiated in 2014 the mapping of Schistosomiasis and Soil Transmitted Helminthiasis (STH). Here, we report the results of the Northern and Eastern health regions, representing a third of the land area and 12% of its total population. All nine departments of the two regions were surveyed and from each, five schools were examined with 50 schoolchildren per school. The parasitological examinations were realized using the filtration method for urine and the Kato-Katz technique for stool samples. Overall 2245 schoolchildren (1116 girls and 1129 boys), mean aged 11.28 ± 0.04 years, were examined. Combined schistosomiasis and STH affected 1270 (56.6%) with variation between regions, departments, and schools. For schistosomiasis, prevalence were 1.7% across the two regions, with no significant difference (p > 0.05) between the Northern (1.5%) and the Eastern (1.9%). Schistosomiasis is mainly caused by Schistosoma haematobium with the exception of one respective case of S. mansoni and S. guineensis. STH are more common than schistosomiasis, with an overall prevalence of 56.1% significantly different between the Northern (58.1%) and Eastern (53.6%) regions (p = 0.034). Trichuris trichiura is the most abundant infection with a prevalence of 43.7% followed by Ascaris lumbricoides 35.6% and hookworms 1.4%. According to these results, an appropriate PC strategy is given. In particular, because of the low efficacy of a single recommended drug on T. trichiura and hookworms, it is important to include two drugs for the treatment of STH in Gabon, due to the high prevalence and intensities of Trichuris infections.

Aim: Diabetes is a metabolic disease most often associated with complications when uncontrolled. The present study aimed to investigate the relationship between diabetes-associated complications, glycemic imbalances and other metabolic deregulation in Gabonese diabetics.Methods: 115 known diabetics were recruited from the Libreville University hospital. We collected anthropometric data and information on associated pathologies. Blood samples collected were analyzed for blood glucose, urea, creatinine, triglycerides, cholesterol fractions and transaminases.Results: Type-2 diabetes was more prevalent in the studied population, representing 90% of cased cases. 41.7% had diabetes cases were associated with hypertension alone. 9.6% of diabetes cases had kidney failure (associated or not with hypertension and/or neuropathy). 87% patients had uncontrolled blood sugar. Creatinine and urea were significantly higher in patients with affections as compared to patients without affections (p<0.0001). In diabetics with controlled blood glucose concentration, only patients with the nephropathy had significantly high levels of creatinine and urea (p<0.05). In diabetics with uncontrolled blood glucose concentration, significantly high levels of creatinine and urea were seen in both patients with hypertension and patient with nephropathy (p<0.001). Conclusion:The high rate of hypertension and hyperglycemia observed suggest that Gabonese diabetics are at high risk for developing nephropathies.