Patient-derived organoids (PDOs) can be derived from malignant ascites and pleural effusions.• PDOs can be used for empirical drug testing of novel therapeutics.• RNA-sequencing analysis indicates gene signature associated with proliferation upon organoid induction.• PDOs represent an efficient model that recapitulates histological features of malignant ascites and pleural effusions.
of 2009. Incidence of shoulder dystocia and delivery outcome was compared pre and post simulation. Chi-squared and Fisher Exact tests along with multivariate logistic regression models were conducted to adjust for potential confounding.
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