Mucoceles are chronic, expanding, mucosa lined pathology of the paranasal sinuses. Frontal mucocele usually presents with the visual complaints such as diplopia, diminution of vision, visual field defect, ptosis, orbital swelling, retro-orbital pain, displacement of eye globe, and proptosis. Very rarely, it can be present as a subcutaneous swelling. This article presents a 58-year-old male patient presenting with an asymptomatic periorbital swelling and a painless forehead mass of 3 years duration. There was a partial ptosis, and an elongated, soft, subcutaneous mass over the forehead. Surgical excision of the mass confirmed the diagnosis of a mucocele. Postoperatively, the patient was asymptomatic. A subcutaneous soft-tissue mass may be the presenting complaint of a frontal mucocele. Careful examination of the surrounding skin may suggest the diagnosis of sinus-related disease and thus direct appropriate investigations.
Bullous pemphigoid (BP) is a chronic subepidermal immunobullous disorder. Studies have demonstrated the presence of antibasement membrane zone antibodies (BP180 & BP230) in the blister fluid using enzyme-linked immunosorbent assay (ELISA). To detect and compare BP 180 and BP 230 autoantibodies in the blister fluid and serum of patients with BP by ELISA method. A total of 30 patients diagnosed as BP and not on treatment were included in the study. Blister fluid and serum were subjected to ELISA, and the results were compared. The sensitivity of ELISA BP 180 was found to be 95.8% in the blister fluid and 88.4% in the serum. The sensitivity of ELISA BP 230 in the blister fluid and serum was 20% and 16.6%, respectively. Association between ELISA antibodies done in blister and serum was analysed using Chi-square test and found to be statistically significant with P value <0.05. Blister fluid is an effective alternative to the serum in detecting BP 180 and BP 230 antibodies, especially in uncooperative and elderly patients with poor venous access.
Automotive industry in continuously expected to produce more fuel-efficient vehicles. Increasing fuel prices and environmental concerns such as emission of CO2 are two areas in vehicle design improvement. There are multiple factors that affect the fuel economy such as rolling resistance, aerodynamic drag, and weight of the vehicle. As the speed of the vehicle increases, aerodynamic drag force becomes the dominating factor affecting the fuel consumption. This aerodynamic drag is a result of the low-pressure region created at the rear end of the vehicle. This low-pressure region is due to the relative square shape of the vehicle at the rear end which generates vortices. This project aims to investigate the effects of an underbody in reducing the aerodynamic drag forces and its effects on fuel usage. The underbody in vehicles is one such area in improving the aerodynamics of a vehicle which can have an impact on overall drag force. Various underbody geometry modifications were carried out on a 3D model of Fiat 500 Electric and Gasoline versions to simulate the effect of underbody geometry on fuel consumption using the CFD simulation tool ANSYS Fluent. It was concluded that the underbody of vehicle influences the overall aerodynamic drag by 20%. Underbody geometry modification helps in reducing the fuel consumption by decreasing the overall aerodynamic drag of the vehicle.
Brainstem hemorrhage following evacuation of chronic subdural hematoma is extremely rare and its pathogenesis is unclear. In our case report, we present a rare case of brainstem hemorrhage following evacuation chronic subdural hematoma. Our patient was a 50-year-old man, with no comorbidities, presented with dorsal midbrain hemorrhage with ventricular extension and symptomatic progression of contralateral small chronic subdural hematoma following evacuation of chronic subdural hematoma. Contralateral subdural hematoma was evacuated and midbrain hemorrhage was managed conservatively. He was discharged with minimal neurologic deficit. Review of literature and pathogenesis of remote hemorrhage after evacuation of chronic subdural hematoma were discussed.
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