Background: Gestational age is the common term used during pregnancy to describe how far advanced is the pregnancy. In the second and third trimesters, estimation of gestational age is accomplished by measuring the biparietal diameter, head circumference, abdominal circumference, and femur length. The transverse cerebellar diameter (TCD) may serve as a reliable predictor of gestational age (GA) of the fetus and a standard against which aberrations in other fetal parameters can be compared.Methods: The study was conducted in the tertiary care teaching hospital from July 2016 to March 2017. 200 pregnant women of gestational age 15-40 weeks of pregnancy referred from Dept of Obs and Gynae for antenatal scan comprised our study sample.Results: Age of women ranged from 18 to 43 years with maximum number of patients aged 26-30 years. Maximum cases with clinical suspicion for IUGR were in gestational age >36-40 weeks (50%). Evaluation of difference in actual and estimated gestational age between normal and actual gestational age showed that for normal pregnancy as well as in IUGR pregnancies mean difference between estimated and actual gestational age was minimum in TCD followed by other established parameters.Conclusions: TCD being a stable parameter irrespective of growth status of fetus, provides a basis for its usefulness as a ratio to predict IUGR and other perainatal outcomes as used in several studies. Thus, despite not being a direct marker for IUGR it can serve as a surrogate marker for detection of IUGR and another adverse perinatal outcome.

Background: Normal pressure hydrocephalus is a very gloomy entity. The objective of this study is to analyse aqueductal velocity parameters by phase contrast MRI CSF flowmetry in Idiopathic Normal pressure hydrocephalus patients (NPH).Methods: This study consists of 72 participants which included 36 patients and 36 matched healthy controls. The study stretched over three years in multicentre tertiary research hospitals using 3T MRI scanner. Both normal MRI sequences and phase contrast CSF flowmetry was done for both group of patients and result analysed using SPSS 17 software.Results: Mean age of patients in our study is 61.07 years. The most common clinical symptom was gait unsteadiness in our study. Most common conventional MRI finding was ventriculomegaly with transependymal seepage of CSF. Amongst CSF flowmetry parameters Aqueductal stroke volume, peak systolic velocity, mean systolic velocity, forward flow volume and backward flow volume were statistically significant in differentiating cases from controls.Conclusions: MRI CSF flowmetry using phase contrast method is an advanced imaging parameter which can non-invasively and reliably detect NPH. Also, it can be used to follow the response to treatment following shunting and can act as a prognostic marker.

Background: This study was done from January 2014 to July 2016, in 128 patients of knee joint osteoarthritis. We assessed epidemiology of osteoarthritis of knee and various MRI findings.Methods: In all the 128 patients radiographs (anteroposterior) were taken in extended and weight bearing position. Staging of osteoarthritis of knee was done using Kellgren-Lawrence scoring system and then we performed magnetic resonance imaging of the knee. All these patients were then interviewed about their clinical symptoms and osteoarthritis of knee was graded by WOMAC scale.Results: Osteoarthritis has a positive correlation with age, female sex and BMI. However occupation of the patient was not associated with any statistical significance. No association was seen between cartilage defects, bone marrow edema, sub chondral cysts, subchondral sclerosis, Baker’s cysts subluxations of tibia and synovitis with clinical features. The patellofemoral compartment of knee joint mostly contributed to the clinical symptoms of the patients in our study population though not being statistically significant (P >0. 05). In tibiofemoral compartment a statistically significant correlation was seen between most of the MRI findings and KL score, however in patellofemoral compartment this correlation is poor.Conclusions: Clinical findings and plain radiographs are still important in evaluating osteoarthritis of knee, MRI plays an important role in imaging the bony and soft tissues of knee as a whole organ, thereby helping in better management and outcome of the disease. Also MRI plays an important role in depicting early changes of osteoarthtis.

Background: Interstitial lung diseases (ILD) are a heterogeneous group of non-neoplastic disorders resulting from damage to the lung parenchyma by varying patterns of inflammation and fibrosis. With high-resolution computed tomography (HRCT) the pattern of lung damage can be mapped accurately which may help to identify specific ILD.Methods: 65 diagnosed cases of ILD by HRCT who were admitted to a tertiary care chest hospital, formed the study group. All these patients also underwent histopathological confirmation as per hospital protocol. The study was done over a period from August 2016 to July 2019. Clinical details, chest x-ray, HRCT and histopathological data was collected and analysed using 2x2 table for detecting sensitivity, specificity, positive predictive value (PPV) and negative predictive values (NPV).Results: For diagnosing ILD like acute interstitial pneumonia (AIP), LIP and RB ILD the HRCT fared equally well in diagnostic utility as compared to histopathological examination. But in certain conditions like non-specific interstitial pneumonia (NSIP) the HRCT performed poorly in terms of PPV as compared to gold standard histopathology. In Bronchiolitis obliterans organizing pneumonia (BOOP) and usual interstitial pneumonia (UIP) again the HRCT performed fairly well as compared to gold standard.Conclusions: HRCT shows good correlation with histopathological diagnosis in identifying a various subtype of ILD and may thus serve a useful non-invasive, imaging biomarker not only for diagnosing a particular ILD but for prognostication and response to treatment.

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