The
cationic Ru–H complex [(C6H6)(PCy3)(CO)RuH]+BF4
– (1) with 3,4,5,6-tetrachloro-1,2-benzoquinone (L1) was found to be a highly effective catalyst for the deaminative
coupling reaction of 2′-hydroxyaryl ketones with simple amines
to form 3-substituted flavanone products. The analogous deaminative
coupling reaction of 2-aminobenzamides with branched amines directly
formed 3,3-disubstituted quinazolinone products. The catalytic method
efficiently installs synthetically useful flavanone and quinazolinone
core structures without employing any reactive reagents.
The Ru–H complex (PCy3)2(CO)RuHCl (1) was found to be a highly effective catalyst for the three-component deaminative coupling reaction of anilines with aldehydes and allylamines to form 2,3-disubstituted quinoline products....
Correction for ‘Concise synthesis of 2,3-disubstituted quinoline derivatives via ruthenium-catalyzed three-component deaminative coupling reaction of anilines, aldehydes and amines’ by Aldiyar Shakenov et al., Org. Biomol. Chem., 2023, https://doi.org/10.1039/d3ob00348e.
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