Hydroxyapatite
(HAp) plates were successfully synthesized using
dodecanedioic acid (DDDA). Following the preparation of an ethanolic
solution of DDDA, solutions of calcium and phosphate were added in
succession to produce a white slurry upon mixing. Subsequent processing
of this slurry under hydrothermal conditions provided HAp plates of
various sizes. Indeed, the plate size could be changed by varying
the quantity of DDDA employed in the synthesis, with larger particles
being obtained in the presence of larger quantities of DDDA. It was
confirmed that a calcium–DDDA complex (Ca-DDD, calcium dodecanedioate)
was formed upon mixing of the DDDA and calcium solutions. The observed
morphological control could potentially be accounted for by the formation
of Ca-DDD. More specifically, during crystal growth, Ca-DDD plays
the role of a nucleation substrate (template), a pH buffer, and a
calcium reservoir. Finally, we demonstrated that the obtained HAp
plates could be employed to prepare a HAp film with high crystallographic
orientation.
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