Objectives: Hematopoietic stem cell transplantation is a life-saving treatment, but donor numbers are lacking in Turkey and elsewhere. Increased awareness of hematopoietic stem cell transplantation among university students might help expand donation. We evaluated the effect of a brief targeted educational intervention on knowledge and attitudes about hematopoietic stem cell transplantation and donation among first-year university students in Turkey. Materials and Methods: There were 301 first-year university students (median age, 18 y) who volunteered: 163 medical students (54%) and 138 law students (46%). Before and after a brief lecture about hematopoietic stem cell transplantation, students answered a 5-item yes-or-no questionnaire regarding (1) knowledge about health benefits of hematopoietic stem cell transplantation; (2) knowledge about stem cell banking and donation in Turkey; (3) knowledge about the transplantation procedure; (4) prior experience and/or willingness to donate blood; and (5) willingness to donate stem cells. Reasons for motivation to donate blood and/or stem cells were categorized. Results before and after the lecture were evaluated with univariate and multivariate analyses. Results: The response rate was 100%. Significantly greater proportions of students had knowledge about hematopoietic stem cell transplantation and willingness to donate blood and stem cells after the lecture. There were no differences between medical and law students before the lecture. After the lecture, a significantly greater proportion of medical students indicated knowledge about health benefits of hematopoietic stem cell transplantation, stem cell banking and donation in Turkey, and the transplantation procedure. Conclusions: Brief education about hematopoietic stem cell transplantation for university students can increase knowledge and awareness about hematopoietic stem cell transplantation and cause more positive attitudes about stem cell donation.
Otoimmünpoliendokrinopati-candidiazis-ektodermal distrofi olarak da adlandırılan otoimmün poliglandüler sendrom tip 1(OPS-1); mukokütanöz kandidiyazis, hipoparatiroidi ve Addison hastalığı olmak üzere üç tane major komponente sahiptir ve 21. kromozomda localize olan AIRE genindeki mutasyonlar bu hastalığın nedenidir. Yirmi bir yaşında Addison hastalığı tanısı olan kadın hasta polikliniğimize rutin kontrol için başvurdu. Hastaya 6 yaşında iken yorgunluk ve hiperpigmentasyon şikayetiyle başvurduğu hastanede Addison hastalığı tanısı konulmuş. Altı ay sonra primer hipoparatiroidi tanısı almış. Fizik muayenede hastanın ağzında mukokütanöz kandidiazis ve sağ el ikinci parmak tırnağında ektodermal distrofi tespit edildi. Hastanın pubik ve aksiller bölgede kıllanması yoktu. Abdominal ultrason incelemesinde asplenizm saptandı. Sonuçta, OPS-1' de ektodermal distrofi görülebilir. Bu nedenle ektodermal distrofili hastalarda OPS-1 açısından dikkatli olmak gerekir.
The primary skeletal lymphoma is a rare disease that accounts for only 0.5% of all extra nodal, The pathogenesis of the lymphoma that occurs in the muscles is not clear. It has been suggested that the muscle lymphoma may originate from abnormal lymph nodes within the muscles. In this report , there is a case about this rare non-hodgkin lymphoma. A 42year-old female patient presented to our clinic with complaints of pain in the left leg. In the bone biopsy from the lesion of the patient; it is seen that atypical cells with diffuse infiltration into adjacent striated muscle tissue The findings were evaluated as diffuse large B-cell lymphoma. Primary extra nodal lymphomas in the skeletal muscle are radiologically similar to osteomyelitis, so in the case of a patient complaining of pain and swelling in the adjacent skeletal muscle, primary extra nodal lymphoma should be considered in differential diagnosis, although it is rare
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