We examined the impact of the preprocedural triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) ratio on risk of in-stent restenosis (ISR). Patients with typical anginal symptoms and/or positive treadmill or myocardial perfusion scintigraphy test results who underwent successful coronary stent implantation due to stable angina were examined; 1341 patients were enrolled. The hospital files of the patients were used to gather data. Cox regression analysis showed that the TG/HDL-C ratio was independently associated with the presence of ISR ( P < .001). Moreover, diabetes mellitus ( P = .007), smaller stent diameter ( P = .046), and smoking status ( P = .001) were also independently associated with the presence of ISR. Using a cutoff of 3.8, the TG/HDL-C ratio predicted the presence of ISR with a sensitivity of 71% and a specificity of 68%. Also, the highest quartile of TG/HDL-C ratio had the highest rate of ISR ( P < .001). Measuring preprocedural TG/HDL-C ratio, in fasting or nonfasting samples, could be beneficial for the risk assessment of ISR. However, further large-scale prospective studies are required to establish the exact role of this simple, easily calculated, and reproducible parameter in the pathogenesis of ISR.
Purpose The purpose of this study was to correlate the right atrial pressure with the blood flow velocity and pulsatility index (PI) values obtained with duplex Doppler sonography of the common femoral vein. Methods Thirty consecutive patients with suspected right‐sided heart failure who had right atrial pressure measurements for correlation were included in the study. The common femoral veins were examined with duplex Doppler sonography. Irrespective of the presence or absence of clinical right‐sided heart failure, patients were divided into 2 groups on the basis of their right atrial pressures. The mean flow velocities and PIs in the common femoral veins of the 2 groups were compared. Results In patients with elevated right atrial pressure (≥G8 mm Hg), the mean minimum flow velocity ± standard deviation (−0.15 ± 0.11 m/second) in the common femoral vein was significantly lower than that in patients with normal right atrial pressure (< 8 mm Hg) (0.01 ± 0.10 m/second) (p < 0.001). There was no significant difference in the mean maximum flow velocities in the common femoral vein between the patients with elevated right atrial pressure (0.25 ± 0.08 m/second) and the patients with normal right atrial pressure (0.21 ± 0.09 m/second). The mean PI in patients with elevated right atrial pressure (7.75 ± 3.19) was significantly higher than the mean PI in patients with normal right atrial pressure (1.55 ± 1.30; p < 0.001). There was a weak negative correlation between the minimum flow velocity and the pressure in the right atrium in patients with elevated right atrial pressure (p = 0.05; r = −0.4760). The amplitude of retrograde waves seen in patients with normal right atrial pressure was significantly smaller than in patients with elevated right atrial pressure (p < 0.05). Conclusions The association of a decreased minimum velocity, especially a negative value, and an increase in PI in the common femoral vein may indicate an elevated right atrial pressure. Sonographic assessment of retrograde flow velocity in the common femoral vein may be useful in monitoring the response to medical treatment to decrease atrial pressure. © 2001 John Wiley & Sons, Inc. J Clin Ultrasound 29:87–91, 2001.
ABSTRACT:Purpose. The purpose of this study was to correlate the right atrial pressure with the blood flow velocity and pulsatility index (PI) values obtained with duplex Doppler sonography of the common femoral vein.Methods. Thirty consecutive patients with suspected right-sided heart failure who had right atrial pressure measurements for correlation were included in the study. The common femoral veins were examined with duplex Doppler sonography. Irrespective of the presence or absence of clinical right-sided heart failure, patients were divided into 2 groups on the basis of their right atrial pressures. The mean flow velocities and PIs in the common femoral veins of the 2 groups were compared.Results. In patients with elevated right atrial pressure (Ն8 mm Hg), the mean minimum flow velocity ± standard deviation (−0.15 ± 0.11 m/second) in the common femoral vein was significantly lower than that in patients with normal right atrial pressure (< 8 mm Hg) (0.01 ± 0.10 m/second) (p < 0.001). There was no significant difference in the mean maximum flow velocities in the common femoral vein between the patients with elevated right atrial pressure (0.25 ± 0.08 m/second) and the patients with normal right atrial pressure (0.21 ± 0.09 m/second). The mean PI in patients with elevated right atrial pressure (7.75 ± 3.19) was significantly higher than the mean PI in patients with normal right atrial pressure (1.55 ± 1.30; p < 0.001). There was a weak negative correlation between the minimum flow velocity and the pressure in the right atrium in patients with elevated right atrial pressure (p = 0.05; r = −0.4760). The amplitude of retrograde waves seen in patients with normal right atrial pressure was significantly smaller than in patients with elevated right atrial pressure (p < 0.05).Conclusions. The association of a decreased minimum velocity, especially a negative value, and an increase in PI in the common femoral vein may indicate an elevated right atrial pressure. Sonographic assessment of retrograde flow velocity in the common femoral vein may be useful in monitoring the response to medical treatment to decrease atrial pressure.
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