CONTEXT: Acne vulgaris is the most common skin disorder in youth and is of multifactorial etiology. Severe forms of acne are often therapy resistant. AIMS: To determine bacteria involved in acne vulgaris and to determine the in vitro antibiotic sensitivity of aerobic isolates. SETTINGS AND DESIGN: Cross sectional study. METHODS AND MATERIALS: Samples from skin lesions of study group (80 patients) and normal skin of control group (20 patients) were collected by sterile swabs. The specimens were used for aerobic and anaerobic culture at 37°C. The isolates were subjected to biochemical tests for identification. All the aerobic isolates were subjected to antimicrobial sensitivity testing by disc diffusion method. RESULTS: High incidence of acne was found in the age group of 13-20 years (76.25%). Males were more affected than females. Pustules (76.25%) were the commonest presentation. Students (71.25%) were more commonly affected. Among aerobic isolates (71.24%), Staphylococcus epidermidis (54.38%) was the most common organism. Among the anaerobes, Propionibacterium acnes (55.17) were the most common. Among the aerobic isolates, most were sensitive to Minocycline followed by Ofloxacin, Azithromycin, Cephalexin, Tetracycline, Cotrimoxazole and Ampicillin. CONCLUSIONS: In the present study, acne affected individuals were young males, especially students, with pustules being the commonest presentation. Staphylococcus epidermidis, the dominant organism isolated was susceptible to Ofloxacin, Minocycline and Azithromycin.
The ability of urinary conduits to absorb glucose was investigated. A solution containing 1% glucose and the inert marker phenol red was put into conduits in diabetic and non-diabetic patients. Samples were withdrawn at intervals for analysis and the fall in concentrations plotted against time. The loops in the patients without diabetes did not absorb glucose, but glucose was absorbed in one of the three diabetics.Ileal loops in patients with diabetes may absorb urinary glucose. This should be checked in any diabetic with urinary diversion before advice is given on long term management. Routine testing of conduit urine for glucose may not be an adequate screen for diabetes in patients with urinary diversions.
The ability of urinary conduits to absorb glucose was investigated. A solution containing 1% glucose and the inert marker phenol red was put into conduits in diabetic and non-diabetic patients. Samples were withdrawn at intervals for analysis and the fall in concentrations plotted against time. The loops in the patients without diabetes did not absorb glucose, but glucose was absorbed in one of the three diabetics.Ileal loops in patients with diabetes may absorb urinary glucose. This should be checked in any diabetic with urinary diversion before advice is given on long term management. Routine testing of conduit urine for glucose may not be an adequate screen for diabetes in patients with urinary diversions.
Diabetics exhibit a great frequency and severity of infection.Recovery of multidrug resistant Pseudomonas aeruginosa and ESBL producing Klebsiella and Escherichia coli are of serious concern. AIMS AND OBJECTIVES: The aims of the study are to establish the Bacteriological profile in Wagner's grades of foot ulcers in Diabetics and foot ulcers in Non-diabetics, Antibiogram of isolates. MATERIAL AND METHODS: A total of 265 samples were collected from two Study Groups. Pseudomonas aerugionasa isolates were subjected to screening of Amp-C β lactamase by disc antagonism test.Klebsiella species and Escherichia coli that were found to be resistant to first, second and third generation cephalosporins were confirmed for ESBL production by Disc Potentiation Test. RESULTS: More number of ulcers (111) were of Grade II in diabetics and the commonest risk factor was found to be Neuropathy (122). Nature of infection in foot ulcers was mostly polymicrobial (35.8%) in Diabetics where as it was only Monomicrobial (100%) in Non-diabetics. All the CONS isolated (59) from diabetic foot ulcers were sensitive to Linezolid and resistant to Penicillin. They were moderately resistant to Cephalosporins (68%) and Fluoroquinolones (59%).Ten of Escherichia coli (32.2%) and 26 of Klebsiella species (44.0%) were ESBL producers. 18 of Pseudomonas spp (27.2%) were positive for Amp C beta lactamase. CONCLUSION: Because of Neuropathy and the altered immune status in Diabetic patients, opportunistic and polymicrobial infections are common in Diabetic foot ulcers. Moreover these patients show Multi Drug Resistant patterns.
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