Squamous cell carcinomas are favored by repeated sun exposure, especially in fair-skinned people who easily get sunburned. There are also genetic diseases including albinism which can promote their appearance early in life and multiple forms. We report the first observation of frontal squamous cell carcinoma with resection and reconstruction using the H-shaped flap in an albino (in Mali). Oculo -cutaneous albinism consulted for a frontal ulceration evolving for 3 years. The initial lesion was an erythematous macula which progressively evolved into a dragging ulceration. She had been treated with three sessions of cryotherapy (liquid nitrogen) without success. Physical examination found a slightly crusty ulceration, circumscribed (2 x 1.6 cm), painful and non-itchy. Otherwise the rest of the clinical examination was normal. A biopsy for pathological examination was performed. The diagnosis of invasive squamous cell carcinoma was confirmed. Surgical treatment was performed (resection and reconstruction with the H-shaped flap) with simple postoperative course and satisfactory results from an aesthetic point of view.
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