A 64-year-old woman was referred to the hospital with complaints of abdomen right side tightness with discomfort for 1 month. Computed tomography scan of abdomen investigation revealed large retroperitoneal mass measuring 18.9 cm × 12.1 cm displacing the inferior vena cava right kidney and renal vessels in right hypochondriac and lumbar regions of the abdomen with large fat components. She underwent surgery, which involves the resection of tumor mass with non-affected surgical margins. These tumors tend to be resistant to radiotherapy or chemotherapy. Among the most important prognostic factor related to survival is surgery with non-affected margins. A review on etiology, pathophysiology, pathological classification, and grading is explained in literature review.
A 50 years old woman was referred to hospital with complaints of bluish black discoloration of skin or multiple ecchymosis since 6 days and skin rashes, pink changes or petechiae changes since 1 week, dark color stools since 3 days. She had a history of COVID-19 positive on past ‘‘3 months’’ back and she received the corticosteroids, antiviral drugs, broad spectrum antibiotics, anticoagulants, and vitamin B and C supplements. Now patient is admitted and investigated for further management. Her bone marrow examination reveals marrow cytological features are compatible with immune thrombocytopenic Purpura and peripheral examination reveals red cells are microcytic hypochromic with elongation forms, platelets are markedly reduced and elevation of CRP, reduction of the Hb, PCV, MCH, MCV, MCHC, APTT, Serum vitamin B12, Lymphocytes and her HRCT-Chest shows CORADS 5, Rapid antigen test shows positive. A review on introduction of the disease, etiology, pathogenesis, pathophysiology, mechanism of thrombocytopenia in COVID-19 patients and grading is explained in literature review.
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