L´insuffisance rénale terminale nécessite un traitement de suppléance notamment l´hémodialyse. Avant l´initiation, le patient et son entourage reçoivent des informations sur la maladie rénale et les possibilités de traitement. Ce travail a pour objectif d´évaluer le niveau de connaissance ainsi que l´opinion de l´hémodialysé et de son entourage sur la maladie rénale chronique et les traitements de suppléances rénales. Il s´est agi d´une étude transversale descriptive qui s´est déroulée du 29 juillet au 19 août 2020 dans l´unité d´hémodialyse du CHU-SO. La population de notre étude était constituée de tous les patients hémodialysés de l´unité d´hémodialyse du CHU-SO et de leurs accompagnants qui ont donné leur consentement libre et éclairé. Les données ont été collectées de façon anonyme à partir d´un questionnaire. La saisie et l´analyse statistique des données ont été faites au moyen du logiciel Epi Info dans sa version 7.2.2.6. Quatre-vingt-et-un patients et 79 accompagnants ont été interrogés. Les âges moyens des patients et leur accompagnant étaient respectivement de 49,7 ans ± 13,5 et 39,6 ans ± 13,2. Tous les patients connaissaient leur pathologie et 94% des accompagnants, les informations sur la maladie de leurs parents. L´hémodialyse était considérée très chère par 95,1% des patients. L´avantage de l´hémodialyse le plus connu par les patients était la qualité de vie améliorée (80,2%) et 15% pensaient également que la transplantation rénale était tout aussi efficace. La majorité des accompagnants (85%) ont déclaré que l´hémodialyse était le meilleur traitement. L´éducation thérapeutique des patients hémodialysés et des accompagnants est importante pour une meilleure prise en charge globale des hémodialysés.

Background: Coronavirus disease mortality is high in people with chronic kidney disease. Method: we present the characteristics and factors associated with mortality of patients hospitalized for Covid-19 and with chronic kidney disease in a descriptive and analytical cross-sectional study of CKD patients admitted to the Lomé Commune Regional Hospital Center (CHR-LC) from March 2020 to August 2021. Results: A total of 127 patients met our inclusion criteria. We found a mortality rate of 48.8% in Lomé (Togo). Factors associated with this mortality in our study were severity of Covid-19 (p < 0.0001), length of hospital stay (p < 0.0001), pulse oxygen saturation (p < 0.0014), GFR stage (p = 0.0003), existence of hyperglycemia (p = 0.0036) and use of corticosteroids (p = 0.0336). Conclusion: Mortality is very high in CKD patients with Covid-19.

Background: Acute kidney injury (AKI) is one of the increasingly described complications of coronavirus infection. Objectives: To identify factors associated with death in patients with acute kidney injury (AKI) during Coronavirus disease (COVID-19) in Abidjan, Côte d'Ivoire. Material and Method: This was a monocentric retrospective analytical study of all patients over 18 years of age with AKI during COVID-19 at the Farah Polyclinic in Abidjan, Côte d'Ivoire. AKI was defined and ranked according to Kidney Disease Improving Global Outcomes (KDIGO) 2012. The data were collected from the medical record and processed using RStudio. Results: Forty-three cases were collected. The average age was 58.5 12 years. The sex ratio (M/F) was 4.4. The main comorbidities were high blood pressure (60.4%) and diabetes (37.2%). AKI was at KDIGO stage 3 in 58%, KDIGO 2 in 21% and KDIGO 1 in 21%. The diagnosis of acute tubular necrosis was retained in 44.2% of patients followed by acute functional kidney injury in 32.6%. Hemodialysis was initiated in 48.8% of cases. The main indication of dialysis was anuria (46.6%). In total, 55.8% of patients died. Factors associated with death were KDIGO stage (p = 0.049), and invasive ventilation (p < 0.001) associated with the risk of death in univariate analysis. Conclusion: Mortality is high in patients with AKI during COVID-19 infection.

HIV infection is a major cause of chronic kidney disease, associated with high morbidity and mortality in sub-Saharan Africa. The objective of this study is to assess the prevalence and risk factors of renal disease at initiation of antiretroviral therapy. This was a descriptive and analytical retrospective study carried out in the infectious and tropical diseases department at Sylvanus Olympio University Hospital. The data have been extracted from the ESOPE software. Kidney disease was defined by a GFR, estimated by MDRD (Modification of Diet in Renal Disease) formula, less than 60 ml/min/1.73 m 2. Risk factors associated with kidney disease were assessed using univariate and multivariate analysis. There were 3118 HIV-infected patients included in our study. The median estimated filtration rate was 94.7 ml/min/1.73 m 2 : 2.9% had an eGFR < 15 ml/min/1.73 m 2. 1303 had kidney disease (41.8%). Most patients (30.8%) were in the WHO clinical stage 1. The median CD4 count was 165/µL [IQR = 72-274/µL]; the median hemoglobin level was 10.4 g/dL [IQR = 8.8-11.9 g/dL]; all patients had thrombocytopenia less than 100.000/mm 3 ; 8.5% had leukocytosis greater than 10.000/mm 3. Most of patients had HIV1. In the multivariate analysis, age greater than 40 years (p < 0.0001), and female gender and hyperleukocytosis greater than 10,000/mm 3 were significantly associated with renal disease. The prevention of kidney disease must go through the identification of its risk factors in the target populations.

Introduction: The morbidity and mortality of patients with heart failure are known to increase rapidly in the presence of renal insufficiency, which is usually the cause but may be a consequence. To organize better prevention of renal failure, we undertook this study to identify the determinants of renal failure in the population of patients with heart failure. Methodology: This was a retrospective descriptive and analytical study of heart failure (HF) cases hospitalized from January 1st to December 31st, 2016, over a period for twelve (12) months at CHU Sylvanus Olympio. Patients who performed cardiac Doppler ultrasound were included in our study. Renal failure was defined as eGFR (estimated glomerular filtration rate) less than 60 ml/min/1.73m 2 . Multivariate logistic regression was performed to investigate associated factors. The dependent variable was DFG status: coded 1 if the GFR is less than 60 ml/min and 0 if not. Results: A total of 216 patients were included. The majority were female (54.17%). The median age of patients was 53 years [IQI = 32 -61 years] with extremes of 15 and 96 years. 16.49% of patients had a GFR of less than 60 ml/min. In multivariate analysis the average standard of living (OR = 2.40, p = 0.0456), diabetes (OR = 2.67, p = 0.0300), hypertension (OR = 5.66, p = 0.0399), alcoholism (OR = 4.00, p = 0.0063) were the main factors in the development of an RF/HF. Conclusion: The average standard of living, diabetes, hypertension, and chronic alcoholism are the determinants of renal failure in HF.