Endameba histolytic a of the gastrointestinal tract is common in developing countries. There are many cases where colonic amebiasis can mimic colonic carcinoma but amebiasis and coexisting carcinoma is exceedingly rare. We present a case of 43 years old male who presented with abdominal pain, generalized weakness and bleeding per rectum. Endoscopic examination showed superficial ulceration with edematous mucosa in proximal, transverse and ascending colon which was indistinguishable from ulceration and amebomas. Histopathological examination of tissue revealed the coexistence of Endameba trophozoites with adenocarcinoma of colon. The organism was demonstrated by Periodic Acid Schiff’s stain with engulfed red blood cell. Our report is to enhance the awareness that amebiasis is may not only mimic carcinoma but can also coexist with carcinoma. After extensive search of literature, our isolated case report might be under tenth of reported cases.
Keywords: Amoebiasis; Endameba histolytic; Carcinoma
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