Angiotensin-converting enzyme inhibitors (ACE-I) are medications within the antihypertensive class that are used by nearly 108 million patients worldwide [1]. A rare but possibly life-threatening adverse effect of ACE-I is angioedema, which occurs due to elevated levels of bradykinin [2]. In this case report, we discuss a patient case where the use of tranexamic acid (TXA), an antifibrinolytic agent, prevented impending intubation due to ACE-I induced angioedema.
CaSe RepoRtCheck for updates was admitted to the intensive care unit with an O 2 saturation of 98% and observed for 24 hours without any interventions (Figure 2). Counseling was provided and ACE-I allergy was documented on electronic medical records prior to discharge.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.