BACKGROUNDCancer of any type is a serious and life-threatening illness, not uncommon in the general population. Cancer survivor can mean any person diagnosed with cancer from the time of initial diagnosis until his or her death. It includes people who are dying from untreatable cancer. Cancer survivor also includes those patients who are receiving or have received treatment with no active disease process and those who are not in the terminal stage of the illness. Cancer survivors tend to develop anxiety, depression and change in their quality of life as they have to make adjustment to many psychological and physical changes as well as financial constraint.

This study was carried out to assess the personality changes of marijuana users and to examine whether marijuana users are prone to psychotic or neurotic features. Purposive sampling method was used for collecting the data. 16 PF and E.P.Q.-R were administered for assessing the personality changes and to detect the development of psychotic and neurotic features for both the groups. The mental condition of the normal individual was worked out by using the General Health Questionnaire 12 items. All the subjects were male because female marijuana users were not available during study period. The study shows that there is difference between the two groups by the primary factors on factor E (Humble vs. Assertive) and M (Practical vs. Imaginative). But there is no difference in Global factors between the two groups. On factor E (Humble vs. Assertive) user tend to accommodate others wishes, and are cooperative and agreeable, willing to set aside their own wishes and feelings. On factor M (Practical vs. Imaginative) users are more oriented to abstract ideas than the external facts practicalities. Being focused on thinking, imagination and fantasy, high scorers generate many ideas and theories and often creative. Extreme scorers can be so absorbed in thought that they can be absentminded and impractical. Highest percentage in extraversion for the control group and highest percentage in neurotic for the case group were found in assessment of three dimensions-psychotic, extraversion and neurotic according to E.P.Q.-R. Extraversion as opposed to introversion, refers to the outgoing, uninhibited, sociable proclivities of a person whereas, Neuroticism refers to the general emotional liability of a person, his emotional over -responsiveness and his liability to neurotic breakdown under stress. Severe and prolong case of neuroticism may lead to the development of psychotic illness in the later stage of life.

Background: Thyroid disorders can induce virtually any psychiatric symptom or syndrome, although no consistent associations of specific syndromes and thyroid conditions are found. Abnormal thyroid hormone levels are common in psychiatric disorders Material & Method: T3, T 4 , TSH levels were measured in a sample of 90 (ninety) cases who attended Department of Psychiatry, RIMS hospital. The sample consists 30 (thirty) cases each from three-group viz., Controls consisting of normal healthy persons, Schizophrenia, and Depression. Data was collected for a period of 1 year from the subjects who were fulfilling the DSM IV TR diagnostic criteria of schizophrenia and depression. All the study subjects were evaluated for socio demographic variables on semi structured Proforma. Thereafter the laboratory assessments of T3, T4, TSH levels were conducted in the Dept. of Biochemistry, RIMS.Result: The blood level of T3 and T4 was seen highest among schizophrenic groups followed by control and depressive groups. Highest level of TSH was noticed in the depressive groups followed by controls and schizophrenia Conclusion: This study shows that there is an abnormality in thyroid hormone levels in the psychiatric disorders of depression and schizophrenia. In depression, T 3 and T 4 levels are lower but higher in case of schizophrenia. TSH is higher in depression and lower in schizophrenia.

Anxiety disorders are relatively common and patients who have been under prolonged medication for anxiety disorders worry about their dependent on the medication in coping with their problems. Due to numerous unpredictable and unstable circumstances in Manipur, people are more prone to develop anxiety disorder (s) and manifests varied anxiety symptoms. Therefore, the present study takes the initiative to evaluate differences between anxiety patients receiving medication alone & medication with progressive muscular relaxation therapy. The sample of the present study consisted of 30 anxiety patients. The cases included in the study are those patients already been diagnosed as Anxiety Disorders and under medication for a minimum duration of 1 year. Anxiety level of the participants were assessed on State and Trait Anxiety Inventory (STAI) at two levels i.e. pre and post sessions on relaxation therapy. Pre assessment is done at the initial stage and final assessment is done after a gap of three (3) months. This study finds insignificant difference among the participants with respect to their different sociodemographic profile. However, there is highly significant difference with regard to anxiety level on pre state anxiety (Mean±SD=54.233±5.073, p value= 0.000) and post state anxiety (Mean±SD=49.93±5.601, p value= 0.000).Likewise, there is highly significant difference with regard to anxiety level on pre trait anxiety (Mean±SD=51.50±6.317, p value= 0.000) and post trait anxiety (Mean±SD=47.93±5.86, p value= 0.000). This study finds that medication along with relaxation therapy is more effective than medication alone in treatment of anxiety patients.

Persons with cancer have to go through many painful conditions, face with new and challenging situations the illness brought to their life. Subsequently, all must cope with new stressors; in dealing with the changed situation (s) they might feel loss of control over their life events. Moreover, if the patients are involved in treatment process, it may add up more stress. However, at times, patients with advanced cancer also do desire information on risks and prognosis. Therefore, determining ways of coping with challenges in life posed by cancer and also comparing psychological wellbeing between patients who do not know (Concealed group) and who know about the diagnosis (Unconcealed group) will be helpful in developing a better treatment plans for cancer patients. MATERIALS AND METHODSA total of seventy six (76) cancer patients visiting Department of Radiotherapy, Regional Institute of Medical Sciences (RIMS), Imphal, during February 2014 to December 2014 were enrolled in this study. The total patients were divided into two groups of equal number i.e. 36 each for concealed and unconcealed groups and both the groups were administered the semi-structured questionnaire, Ways of Coping (Folkman S and Lazarus RS, 1985) and The Psychological Wellbeing Index (Dupuy, 1984) and the data were analysed using SPSS version 20.0. RESULTSComparison on the patients' ways of coping and also on psychological wellbeing schedule shows no significant difference between the two study groups i.e. concealed and unconcealed groups. Findings on ways of coping subscales are confronting (p=.340), distancing (p=.928), self-control (p=.808), seeking social support (p=.868), accepting responsibility (p=.692), escape-avoidance (p=.941), planful problem solving (p=.106), and positive reappraisal (p=.390), and relation between the two study groups on psychological wellbeing schedule subscales are anxiety (p=.513), depressed mood (p=.700), positive wellbeing (p=.429), self-control (p=.571), general health (p=.947), vitality (p=.877), and global score (p=.671).