Transporting content in most biological systems is done through peristaltic transport phenomenon, examples of which include urine transport from kidney to bladder, swallowing of food through esophagus, the movement of chyme in small intestine, lymph transport in the lymphatic vessels, and in the vasomotion of small blood vessels such as arterioles. The present investigation simulated a transient peristaltic transport by developing a model based on fluid–solid interaction (FSI) method. The conduit in which peristaltic flow occurred was assumed to be axisymmetric. The propagating wave was simulated by prescribing a set of displacements, along the radial direction, on the wall. Both fluid and solid domains underwent large deformations as load applied. Due to large deformations, the adaptive discretization was considered. The ADINA 8.5 software, as finite element analytical software, was applied to study peristaltic transport. The results indicated that the present numerical method can properly introduce the features of the flow. The obtained results reveal that as amplitude ratio increases, axial velocity will increase, resulting in an increase in volume flux. Volume flux fluctuates through the passage of time in a cycle and along a wavelength. An increase in index of non-Newtonian fluid results in a decrease in velocity and increase in wall shear stress. It is observed that by increasing the amplitude of propagating wave, reflux will be increased; meanwhile, peristalsis works as a more efficient pumping process against the pressure applied as a boundary condition. The discussion on reflux according to its physiological importance seems to be helpful, thus the net displacement of the fluid particles after the transit of a single wave was calculated.
Although the demand of donor hearts for patients with end-stage heart failure is growing, its supply has remained constant. Ventricular assist devices (VADs) provide a chance of finding donor heart by increasing waiting period. In this study, the main goal is to employ an industrial method (point-by-point method) for designing blades profile with a simplified geometry which can be produced by conventional manufacturing methods. In this study, a centrifugal continuous-flow rotary pump is designed and the effects of components’ different geometries on the left ventricular assist devices (LVADs) function are investigated. Moreover, both hydraulic performance and blood damages (hemolysis index (HI)) caused by the pump are considered as design criteria. ANSYS CFX 17 is used to analyze the performance of the designed LVAD. Additionally, the geometry of components are investigated based on fulfilling the required performance of the LVAD while reducing the blood damage level. Comparing the designed VAD with the commercial ones shows that the designed blade further improves the performance of the centrifugal LVAD. Therefore, designing the impeller’s blade profile with point-by-point method seems to be promising. Simplicity in manufacturing is considered to be a big advantage for a design which also leads to lower manufacturing costs. This study demonstrates how industrial design methods can be employed to design simple-to-manufacture impellers which are suitable for LVADs.
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