In the editorial which appeared in the July‐August, 1962, issue of this journal, the untoward effects and possible danger of various cholesterol‐lowering agents were discussed, and only dietary modifications were considered a safe approach. In the discussion of sitosterols, the authors of the editorial stated that no toxic effects had as yet been reported. However, they made reference to a report by Curran and Costello in 1956 and stated: “There is evidence that [sitosterols] can induce atherosclerosis in experimental animals.” The implication that this may also be the case in man is apparent from the leitmotiv of the editorial.
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