A method for 99mTc-diethylenetriaminepentaacetate (DTPA) gamma-camera renography is presented. From each renogram, an uptake index (UI) proportional to the single-kidney glomerular filtration rate (SKGFR) is defined. If the proportionality factor between UI and SKGFR is the same in all patients, UI can be used as an accurate measure of SKGFR. In order to test this, 99mTc-DTPA renography was performed in 101 patients with glomerular filtration rates (GFR) varying between 4 and 172 ml/min. The sum of the right- and left-kidney UIs correlated well with the total GFR calculated from the simultaneously measured plasma clearance of 99mTc-DTPA after a single injection. The correlation coefficient was 0.97. The method was tested in a prospective study of 57 patients. The total GFR estimated from the renograms was not significantly different from the GFR calculated from the plasma clearance of 99mTc-DTPA. The coefficient of variation--a combination of inaccuracy and imprecision in the estimates as well as in the reference values-was 11.8% at a GFR of 100 ml/min. It is concluded that, in adults, the SKGFR can be calculated as part of the clinical routine from 99mTc-DTPA gamma-camera renography without determining the injected dose or collecting urine or blood samples. Normal values for some parameters of the renogram obtained in 25 normal subjects are given.
Fourty-three eyes with active dendritic keratitis, nearly one third of which had failed to respond to other antiviral agents, were treated with acyclovir with or without preceding debridement. The patients were randomly selected. No statistical difference could be demonstrated between the 2 groups in terms of rate of healing or in efficacy of cure. Acyclovir also seemed to be effective in stromal corneal lesions. There were only minor side effects.
Department ofOphthalmology3 (Heads: V . Dreyer, J. KLAUS 60 JENSEN', MICHAEL MOWN2, FINN EISGART3 and TORLEIF PUGESGAARDZAfter resection in the eye region, skin closure is most often performed with non-absorbable single knots. To investigate how far intracutaneous skin closure with Dexon@ absorbable suture material could demonstrate advantages to the traditional suturetechnique, 57 patients with senile entropions of the lower eyelid were randomized into one of two treatment groups. After a scaphoidal skin resection and resection of fibers of orbicularis muscle, the skin closure was performed with either continuous intracutaneous Dexon 6 or single knots of silk. This study demonstrates that both methods are easy and safe, but a superiority of the technique with absorbable intracutaneous skin closure was found in regard to immediate cosmetic satisfaction and timecomsumption at controls, if necessary, because removal of suture material is not necessary.Key words: absorbable intracutaneous skin closureskin resection of the lower eyelidentropioncosmetic and economical benefit.Entropion of the lower eyelid is commonly seen in man over the age of 70. T h e majority of cases needs surgical treatment. I n the years more than 90 different techniques have been described for correction of the disorder. In the majority of Received on November 12th. 1982. 947 AO* References Salthouse T N & Matlaga B F (1976): Polyglactin 910 suture absorption and the role of Lorentzen M, Eldrup J & Wandall H H (1981): Syntetisk absorberbart suturmateriale. cellular enzymes. Surg Gynecol Obstet 142: 544-550. Ugeskr zeg 143,3443-46 (in Danish).
A non-selected group of 50 patients with recurrent herpetic keratitis, subclassified into groups of stromal or epithelial forms was typed for HLA-ABC antigens. In none of the groups was a statistically significant association to a certain HLA antigen found. When these data are combined with other reviewed reports on HLA types in recurrent herpetic keratitis, a statistically significant association between HLA-B5 and the whole group of recurrent herpetic keratitis, as well as between the subgroup of recurrent stromal keratitis, could be demonstrated. Recurrent epithelial keratitis showed an insignificant association to this antigen.
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