treatment utility increments were included in three submissions from published EQ-5D trial data (n¼2) or a time trade-off study (n¼1). All seven submissions also included various other (dis)utility values (e.g. post-treatment health states, adverse events, comparator treatments) derived from various sources (e.g. published estimates, expert opinion, assumptions). In general, the NICE committee accepted assumptions and alternative sources, including using proxy condition data, when considered appropriate by the ERG and patient/clinical experts. CONCLUSIONS: NICE HST appraisals include a range of utility values and sources, in part due to the lack of evidence in very rare conditions, and NICE are accepting of assumptions and alternative sources.
healthcare utilization than the general elderly population, and their cause of health care use was different from the general elderly population. Strategies focused on this vulnerable population should be considered by policymakers.
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