It is critical to design a novel and simple bifunctional sensor for the selective and sensitive detection of ions in an aqueous media in environmental samples. As a result, in this study, tetraphenylethene hydrazinecarbothioamide (TPE-PVA), known as probe 1, was successfully synthesized and characterized as having impressive photophysical phenomena such as aggregation-induced emission (AIE) and mechanochromic properties by applying mechanical force to the solid of probe 1. The emission of the solid of probe 1 changed from turquoise blue to lemon yellow after grinding, from lemon yellow to parakeet green after annealing at 160 °C, and to arctic blue after fuming with DCM. Such characteristics could lead to a variety of applications in several fields. The probe was implemented and demonstrated remarkable selectivity and sensitivity toward mercury(II) and silver(I) ions by substantially switching off emission over other cations. Following an extensive photophysical analysis, it was discovered that detection limits (LOD) as low as 0.18344 and 0.2384 μg mL –1 for Hg 2+ and Ag + , respectively, are possible with a quantum yield (Φ) of 2.26. Probe 1 was also explored as a Hg 2+ and Ag + paper strip-based sensor and kit for practical use. The binding mechanisms of probe 1 (TPE-PVA) with Hg 2+ and Ag + were confirmed by 1 H NMR titration. These results could lead to the development of reliable onsite Hg 2+ and Ag + fluorescent probes in the future.

It is challenging to work on the detection of toxic anions and pollutants directly from aqueous media by using organic molecules. The ability to detect MnO4− selectively and sensitively is essential to improving human health and protecting the environment. As a result, a Tetraphenylethylene‐based chemosensor was successfully synthesized and fully characterized with modern spectroscopic techniques and applied as a new rapid naked‐eye detection for the MnO4− in a mixed aqueous media ACN: H2O (v/v=1/9) by significantly switching off an emission in a mixed aqueous media over another anion. Chemosensor has been thoroughly studied, which shows remarkable photophysical properties such as aggregation‐induced emission (AIE) and mechanochromic phenomena. The linear regression (R2) is ≈ 0.98 μgmL−1 and the LOD (the detection limit) as low as 0.150418 μgmL−1 is possible for MnO4−. This work demonstrates structure‐property and application relationships of TPEgen scaffolds and connects topics such as AIE, mechanochromic phenomenon, and naked‐eye fluorescence sensing. The current study‘s fundamental knowledge helps improvement in the fields of TPEgen, anion coordination triggered emission and naked eye fluorescence sensing. As a result, a chemosensor can be developed into a prospective luminescent sensor for detecting MnO4−, as well as onsite detection by using the paper‐based sensor.

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A tetraphenylethene‐based organic material (TC) was synthesized to demonstrate mechanochromic memristive properties. The synthesized material shows aggregation‐induced emission and mechanochromic properties. The solvent optimization study reveals that the ethyl acetate‐based TC switching layer shows good resistive switching (RS) properties. To get the mechanochromic memristive properties, different external stresses (ground, heat, and fume) were applied to the TC materials, and these materials were used for the fabrication of switching layers. The results asserted that ethyl acetate and grinding‐based TC devices show good digital‐type RS effects and non‐volatile memory properties. On the other hand, heating and fuming‐based TC devices show analog and quasi‐digital type RS effects, respectively, and mimic various biological synaptic properties such as potentiation‐depression, excitatory postsynaptic current, and paired‐pulse facilitation index. The present investigation is important to fabricate stimuli‐responsive memory and artificial synaptic devices for futuristic non‐volatile memory and neuromorphic computing applications.

: The main component of the sex pheromone of many lepidopteran pests, (4E,10Z)-4,10-tetradecadienyl acetate (1) has been synthesized stereoselectively by using a simple route with 4-pentynol as a starting material. The stereoselective formation of the 4E double bond is based on the stereospecific reduction of internal alkyne with lithium aluminium hydride (LAH) while Wittig reaction was used to achieve 10Z double bond in the target pheromone component. The GC purity of the final acetate was achieved 97.87% while isomeric purities are more than 99%. The green chemistry principle shows a new concept towards for the multistep pheromone synthesis via green metrics calculations.

Ethyl 2-cyano-3-(4-(1,2,2-triphenylvinyl) phenyl) acrylate (TPE-SKJ), a newly synthesized luminogen based on tetraphenylethene, with single crystal analysis exhibits photophysical phenomena such as aggregation-induced emission (AIE); reversible mechanochromic, solvatochromic, organic light emitting diode; and chemical sensing in aqueous media with great selectivity and a low limit of detection. The synthesized material demonstrates high selectivity and sensitivity capacity for sensing MnO4 – in mixed aqueous media (water/acetonitrile, v/v, 9/1). The detection limit for MnO4 – was found to be 0.086009 μg mL–1 with a quantum yield (Φ) of 11%. Moreover, we employed TPE-SKJ material in an organic light-emitting diode (OLED) as an emissive layer. The device shows a maximum of 1.62% external quantum efficiency, higher than nondoped emitting layer-based green OLEDs. The present results will encourage ongoing research into the design of novel stimuli-responsive organic materials with switchable properties based on their supramolecular interactions for numerous applications.

Schematic illustration of the drug delivery mechanism.

The present study shows the chemical profile, antimicrobial, antiproliferative, and apoptotic effects of Stemodia viscosa extracts. Thirteen bioactive compounds were identified in the 80 % ethanolic extract by GC/MS analysis. The acetone extract exhibited a higher content of flavonoids and phenols of 805.10 μg QE/mg DW and 89.31 μg GAE/mg DW extracts, respectively. Furthermore, the acetone extract possessed the highest antioxidant activity (IC50=9.96 μg/mL). The 80 % ethanolic extract exhibited significant antimicrobial activity; the highest activity was observed against Staphylococcus aureus with a zone of inhibition of 25±0.51 mm, MIC value of 4 mg/mL, and MBC value of 8 mg/mL. The antiproliferative results revealed the presence of anticancer activity with an IC50=91.562 and 74.362 μg/mL against the B16F10 skin and COLO205 colon cancer cells, respectively. The flow cytometric analysis shows that the plant extracts cause cancer cell death through the induction of apoptosis. Our findings confirmed that Stemodia viscosa is a potential source of biologically active compounds.