Acute renal failure occurring in a 24-year-old primigravida with eclampsia and HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome is described. She also had transient disseminated intravascular coagulation. Hemodialysis, fresh blood transfusions, and antihypertensive therapy were administered, and resulted in complete recovery. Kidney biopsy revealed acute tubular necrosis.
Shankha Bhasma is a calcium containing formulation which is widely prescribes in practice since ancient time. In the classics of Rasa shastra, Shankha Bhasma recognized as a sole medicines primarily in the treatment of (gastrointestinal disorders) like Amlapitta(~hyperacidity), Grahani(~irritable bowel syndrome), Udarshula (~abdominal colic), Parinamshula(~duodenal ulcer) and Atisara(~diarrhoea). Moreover, Shankha Bhasma provides a good supplementation of calcium as properly manufactured Bhasma. Here an attempt has been made to compile the formulations of Shankha Bhasma in context of different classics, therapeutic indications and recent research works etc. Total 46 formulations are found during the study. By this effort formulations of Shankha Bhasma can be found collectively and could be used widely to get better efficacy to cure the many diseases.
There are many single drug and compound formulations prescribed for Jwara (~ fever) in Ayurvedic classics. Tribhuvanakirti Rasa (TKR), Godanti Bhasma (GB) and Sudarshana Ghana Vati (SGV) are widely used compound formulations that are separately indicated for the treatment of Jwara (~fever) in different dosage schedules. In Ayurvedic Formulary of India Tribhuvana-Mishrana (TM) has been chiefly indicated in treatment of Sarva Jwara (~ fever). Therefore, in this study comparative antimicrobial activity of TM and its individual ingredients viz. TKR, GB and SGV were evaluated against four fever-causing microbes such as gram-positive bacteria Staphylococcus aureus and the gram-negative bacteria Salmonella typhii, Escherichia coli and Pseudomonas aeruginosa. The aqueous extract of all the four samples (formulation as whole and the three individual ingredients separately) in a dose 125mcg/ml were tested for their antimicrobial activity against four different microbes by agar well diffusion method. The study shows that TM and its ingredients independently show significant antimicrobial activity. S. aureus was found to be most sensitive to SGV and moderately sensitive to TKR and TM while S. typhii was found to be most sensitive to TM as compared to others. TKR was found to be most effective against E.coli while SGV and TM both showed significant antimicrobial effect against E. coli. TM could provide an alternative to synthetic antibiotics against human microbial infections.
Ayurveda is the oldest system among all life sciences, originated in India thousands of years ago. It is an ancient Indian practice of holistic medical care that centers on the equilibrium of body, mind and soul. Dosha (vitiating factors), Dhatu (tissue elements) and Mala (waste products) are the basic building elements of the body. Their continuous and proper flow in the body requires hollow spaces or channels. These channels are called as ‘Srotas’ in Ayurvedic classics. Thirteen types of Srotas are described in Charaka Samhita; Pranavaha Srotas is one of them. Pushkara Moola (Inula racemosa Hook.f.) is herb used in traditional medicine in India for a long time to cure the ailments of Pranavaha Srotas Vikara. According to Bhava Prakash, it has the properties of Katu, Tikta in Rasa, Ushna in Virya and pacifies the Vata-Kapha Dosha. Acharya Charaka described it in Shwasahara and Hikkanigrahana Mahakashaya; Acharya Sushruta in Phala Vagra and Acharya Vagbhatta in Hidhma Nigrahana. According to Charaka Samhita it is the best Dravya of Hikka, Shwasa, Kasa and Parshvashula. By these properties, it seems to quite naturally antagonize the Shwasa Roga, which is Kapha-Vata predominant disease. Hence it is needed to evaluate the efficacy of Pushkara Moola in Pranavaha Srotas Vikara.
Chanaka or Chick pea is an old world pulse and considered to be better than other pulses because of good source of carbohydrate and protein, and protein quality is considered to be better than other pulses. It has significant amount of all the essential amino acids. It is rich in unsaturated fatty acids such as linoleic and oleic acids. Beta-sitosterol, campesterol and stigmasterol are important sterol present in Chanaka. According to contemporary research based studies show that chick pea fiber source-lowering the risk of cardiovascular disease, diabetes, obesity and other lifestyle disorders. Ancient lexicons say that it is the best among all grams and advocates its use on daily basis. Review on Chanaka (Cicer arietinum Linn.) was collected from Kosha, Nighantus and data search on the basis of their synonyms and pharmacological properties. This review throws light on some of the important aspect of Chanaka as an effective health promoter as well as its uses in various lifestyle disorders, which will be more valuable for future researchers and practitioners.
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