By using an ickel complex with an N-phosphinomethyl-N-heterocyclic carbene ligand (NHC-P), the reducing ability and thermals tability of the complex were improved considerably comparedt ot he previously reported bipyridine and bisphosphine complexes, and acrylate salt was prepared from ethylene and CO 2 with the highest TON ever reported for nickel systems even without using metallic zinc.O xidativec yclization of ethylene and CO 2 on the NHC-P nickel complex was found to proceed very rapidly compared to previoussystems.[**] NHC = N-heterocyclic carbene.Supporting information and the ORCID identification number(s) for the author(s) of this article can be found under: https://doi.
Product selectivity control for the synthesis of imidoylindoles and 4-alkylidenedihydroquinazolines from N-imidoyl-o-alkynylanilines via silver triflate-catalyzedc ycloisomerization or tetrabutylammonium fluoride-promoted cyclization is described. Thep roduct selectivity depends mainly on the cata-lyst/promoteru sed, ando nt he substituents on the alkyne and amidinef unctionsoft he substrates.
Brønsted acid-promoted intramolecular hydroarylation of alkynylbenzenes carrying an arylalkyl group at the ortho-position leads to alkylidenedibenzo[a,d]cycloheptenes, -octenes and -nonenes in up to quantitative yield with complete regioselectivity. The scope and limitation of this reaction and application to the synthesis of tricyclic antidepressants are described.
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