A mong women worldwide, the second most common gynecologic malignant neoplasm and the third most common cause of cancer death is cervical carcinoma (1). The main histologic types of cervical carcinoma, squamous cell carcinoma and adenocarcinoma, account for approximately 75% and 15% of all cervical cancers, respectively (2-4). The International Federation of Gynecology and Obstetrics (FIGO) stage, histologic type and grade, parametrial invasion, lymph node metastasis, and tumor diameter are important prognostic indicators of cervical carcinoma (2-6). Selecting and planning optimal treatment and predicting recurrence-free survival (RFS) depend on accurate preoperative assessment of these factors in patients with cervical carcinoma.To evaluate the aggressiveness of cervical carcinoma, including parametrial invasion, lymph node metastasis, and distant metastasis, MRI is widely used ( 7), but
SLUG expression could be correlated with TP53 mutational status and could be involved in therapeutic resistance resulting in tumour recurrence. A high expression level of SLUG can be an indicator of recurrence and a therapeutic target for long-term remission in high-grade endometrial carcinomas.
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