20 mg of TAC- was well tolerated. Significant disease stabilization (12/21 pts, 57%), 2 late PRs, and prolonged MS (19.2 months) suggest that TAC-101 provides meaningful patient benefit.
The objective of this study was to identify predictors of self-reported family health history of breast cancer in an ethnically diverse population of women participating in a breast cancer screening program. Participants completed a self-administered questionnaire about their demography, health, breast health and family health history of breast cancer. The association between family health history of breast cancer and categorical variables were analyzed using the T test, chi square, and multi-nominal logistic regression. Those who were least likely to report a family history of cancer were African Americans (p = 0.02), and immigrant women from South America (p < 0.001) and Africa (p = 0.04). However, 34.4 % reported having a second-degree maternal relative with breast cancer compared to 6.9 % who reported having a second degree paternal relative with breast cancer. Therefore, there is a need to increase efforts to educate families about the importance of collecting and sharing one's family health history.
B31 Background Washington D.C. has the highest breast cancer mortality rate in the country(30.3 per 100,000 )*. Project Early Awareness is a breast health education program of Howard University Cancer Center supported by the Prevent Cancer Foundation that serves to address this disparity. The program is designed for 10th-12th grade students in Washington, D.C.. Methods PEA sessions follow a standardized format. The class begins with a young breast cancer survivor’s story, followed by information on breast health topics including risk factors, breast growth and development, clinical breast exams, and mammography. The students are shown an age and culturally appropriate video on how to perform a breast self-exam. Students are then given breast models to practice breast self-exam techniques. The session ends with a question and answer period and a discussion on myths about breast cancer. At the completion of the program, they are handed an information packet to take home and share with their female relatives. Results Since 2001, 2,880 public high school students and their relatives have received breast health information through PEA. Pre and post-test evaluations have been enormously positive, showing a measurable impact in knowledge for the girls attending. Overall, the program generated improvements in specific knowledge elements. A 69% improvement was shown when asked if the age of menarche was a risk factor. The overall increase in self-efficacy for BSE was 39%. Conclusion The high breast cancer mortality rates of African American women living in the District of Columbia mandates the implementation of programs such as this, which focus on long term solutions towards reducing health disparities. PEA is able to reach these young women in a culturally sensitive manner and increase awareness, as well as the understanding of the key screening tools available to women as they age. *American Cancer Society, Surveillance Research , 2007 Citation Information: Cancer Prev Res 2008;1(7 Suppl):B31.
Background: Mammography screening is associated with reduction in mortality from breast cancer. Women with lower socioeconomic status have increased burden from breast cancer which may be attributable to lower access and uptake of screening. The impact of family support in promoting uptake of breast cancer screening among women with low socioeconomic status is not well understood. Aim: We sought to examine whether marital status influences adherence to scheduled free breast cancer screening with clinical breast examination and mammography among uninsured inner city women. Methods: Howard University Cancer Center offered free breast cancer screening (clinical breast examination and mammogram) for uninsured women who are aged 40 and older in the Washington DC area. Participants were referred from community health organizations’ outreach programs in Maryland, District of Columbia and Maryland. Our analytic cohort comprises patients who were scheduled for free breast cancer screening from July 2009 to June 2010. The participants were categorized as non-adherent (no shows) if they did not cancel their appointments and did not show up for the breast cancer screening. We used Poisson regression models to evaluate the association of race with adherence to the scheduled breast cancer screening and adjusted for potential confounders. We calculated Relative Risks (RR) for no shows and 95% Confidence Intervals (CI). Results: A total of 460 patients were scheduled for screening. The mean age was 49.7 years; 195 (43.4%) were Hispanic and 215 (47.9%) were black. 186 (41.3%) patients were married and 264 (58.7%) were not. Married patients were less likely to be born in the United States (6% vs 21%; P < 0.0001) but were comparable in age with unmarried patients (mean age = 49.4 years vs 50.4 years; P = 0.239). 345 (75%) patients showed up but 115 (25%) were non-adherent for their scheduled appointment. When compared with unmarried patients, married patients were less likely to be non-adherent to their breast cancer screening appointment, adjusted RR = 0.58; 95%CI: 0.40 – 0.84, P value = 0.004. Conclusions: Although a quarter of uninsured women are non-adherent for their free breast cancer screening appointments, married women are less likely to be non-adherent. This suggests that educational outreach programs targeting men may be a potential mechanism to increase uptake of breast cancer screening among underserved women. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 1821. doi:10.1158/1538-7445.AM2011-1821
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