ASD is a disabling condition. Prospective analysis of consecutively enrolled patients with ASD demonstrated that PT and PI-LL combined with SVA can predict patient disability and provide a guide for patient assessment for appropriate therapeutic decision making. Threshold values for severe disability (ODI > 40) included: PT 22° or more, SVA 47 mm or more, and PI - LL 11° or more.
Background Although spine surgery is frequent in older adults, the incidence, risk factors, and consequences of delirium in this population have not been well characterized. This is important since spine surgery is increasingly common, pain is a prominent symptom, and postoperative delirium may be preventable. Methods We enrolled 89 adults >70 y/o undergoing spine surgery in a prospective observational study. Postoperative delirium and delirium severity were assessed using validated methods, including the Confusion Assessment Method (CAM), CAM-ICU, Delirium Rating Scale-Revised-98, and chart review. Hospital-based outcomes were obtained from the medical record, and hospital charges from data reported to the state. Results Thirty-six patients (40.5%) developed delirium after spine surgery, with 17 (47.2%) having purely hypoactive features. Independent predictors of delirium were lower baseline cognition, higher average baseline pain, more IV fluid administered, and baseline anti-depressant medication. In adjusted models, the development of delirium was independently associated with increased quintile of length of stay (OR 3.66; 95%CI 1.48–9.04; p=0.005), increased quintile of hospital charges (OR 3.49; 95%CI 1.35–9.00; p=0.01), and decreased odds of discharge to home (OR 0.22; 95%CI 0.07–0.69; p=0.009). The severity of delirium was associated with increased quintile of hospital charges and decreased odds of discharge to home. Conclusion Delirium is common after spine surgery in older adults, and baseline pain is an independent risk factor. Delirium is associated with increased length of stay, increased charges, and decreased odds of discharge to home. Thus, prevention of delirium after spine surgery may represent an important quality improvement goal.
Study Design.A retrospective analysis of a prospective, multicenter database.Objective.The aim of this study was to evaluate the health impact of symptomatic adult spinal deformity (SASD) by comparing Standard Form Version 2 (SF-36) scores for SASD with United States normative and chronic disease values.Summary of Background Data.Recent data have identified radiographic parameters correlating with poor health-related quality of life for SASD. Disability comparisons between SASD patients and patients with chronic diseases may provide further insight to the disease burden caused by SASD.Methods.Consecutive SASD patients, with no history of spine surgery, were enrolled into a multicenter database and evaluated for type and severity of spinal deformity. Baseline SF-36 physical component summary (PCS) and mental component summary (MCS) values for SASD patients were compared with reported U.S. normative and chronic disease SF-36 scores. SF-36 scores were reported as normative-based scores (NBS) and evaluated for minimally clinical important difference (MCID).Results.Between 2008 and 2011, 497 SASD patients were prospectively enrolled and evaluated. Mean PCS for all SASD was lower than U.S. total population (ASD = 40.9; US = 50; P < 0.05). Generational decline in PCS for SASD patients with no other reported comorbidities was more rapid than U.S. norms (P < 0.05). PCS worsened with lumbar scoliosis and increasing sagittal vertical axis (SVA). PCS scores for patients with isolated thoracic scoliosis were similar to values reported by individuals with chronic back pain (45.5 vs 45.7, respectively; P > 0.05), whereas patients with lumbar scoliosis combined with severe sagittal malalignment (SVA >10 cm) demonstrated worse PCS scores than values reported by patients with limited use of arms and legs (24.7 vs 29.1, respectively; P < 0.05).Conclusions.SASD is a heterogeneous condition that, depending upon the type and severity of the deformity, can have a debilitating impact on health often exceeding the disability of more recognized chronic diseases. Health care providers must be aware of the types of SASD that correlate with disability to facilitate appropriate diagnosis, treatment, and research efforts.Level of Evidence: 3.
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