Background: Awareness to health hazards and biosafety precautions among laboratory workers is an important aspect. Technicians handle blood or any biological sample may be at risk for accidental injury or exposure. They are exposed to a large pool of specimens from patients suffering from infections such as hepatitis B virus and human immunodeficiency virus. The lack of awareness regarding biosafety issues results in improper handling and/or dangerous laboratory practices during sample collection, processing, and discarding of specimens, potentially making laboratory technicians more exposed to pathogens. Objective: The aim of this study was to find out the level of awareness and biosafety measures taken by laboratory technicians during their routine work in a tertiary-care center. Material and Methods: A cross-sectional study was conducted at Geetanjali Medical College and Hospital (Central Lab), using a standardized and basic questionnaire, which enquired about awareness and precautions taken by technicians during laboratory work. All (N = 24) technicians enrolled in this study were from departments of pathology, biochemistry, microbiology, blood bank, and sample collection room. Results: Of 24 laboratory technicians, maximum (33.3%) technicians were from pathology department followed by biochemistry (25%) department. According to age, the youngest technician was of 24 years and the oldest was of 46 years. On the basis of their response regarding awareness, knowledge, and biosafety precaution questions, of 24 technicians, 8 (33.3%) were found aware of universal work precaution, 18 (75%) were found immunized with hepatitis B vaccine, and 18 (75%) were found to leave the laboratory without following proper hand wash rule after finishing duty. Conclusion: Knowledge of all the technicians is adequate but there is lack of awareness and practicality among them. There is need to develop standard operating procedures with biosafety training programs and self-hygienic procedures for laboratory workers.
Background: In the assessment of female infertility, prolactin and thyroid hormone measures, notably thyroid-stimulating hormone (TSH), have been regarded as essential milestones. Numerous elements of pregnancy and reproduction are impacted by thyroid dysfunction. Aims and Objective: To compare the levels of thyroid hormones with those of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin in women of reproductive age who are infertile. Materials and Methods: In this retrospective study, 50 fertile women between the ages of 20 and 45 are compared to 110 infertile women who visit our institute’s Gynec OPD. There were 110 infertile women, of which 40 had secondary infertility and 70 had primary infertility. Using chemiluminance immunoassay, the levels of thyroid hormones and infertility hormones are assessed in all individuals. Results: TSH and prolactin had a favorable correlation with one another. In groups of infertile women, they had a negative correlation with LH, FSH, and T3. Therefore, we can conclude that the etiopathogenesis of infertility is strongly influenced by hyperprolactinemia and hypothyroidism. Conclusion: Hypothyroidism is highly prevalent in infertile females in the current study. Menstrual abnormalities brought on by these illnesses may result in infertility. In addition connected to hyperprolactinemia, these individuals frequently experience ovulatory failure. Therefore, the evaluation of serum TSH and prolactin levels is necessary for all infertile women to undergo, especially those who report with menstrual abnormalities.
Background: The sialic acid level is significantly higher in full term cord firbrinogen than in controls and higher in premature than term samples and degree of hypersialation of fetal fibrinogen is a function of gestational age,prenatal diagnosis and confirmation of infantile sialic acid storage disease have been carried out by amniocentesis. Aims & Objectives: To correlate the physiological stress occurring during different trimesters of pregnancy with circulating level of serum sialic acid. Methodology: In this study 30 blood samples were collected from healthy pregnant women in each trimester of pregnancy of age group between 18-35 years along with age and sex matched non pregnant control group. The blood samples was collected from all participants and analyzed for Serum sialic acid ,total protein, albumin and Blood sugar. Results: The mean concentration of serum sialic acid (Micmol/dl) in non pregnant control was estimated to be 119.1±4.68 as compared to 138.8± 4.57,155.76± 5.1, 171.18± 6.7 in first, second and third trimester of pregnancy respectively. Conclusion: The level of total sialic acid is found to be elevated as the pregnancy advances. This increase in maternal circulating serum TSA levels can be attributed to the immunological and metabolic adjustments that the pregnant women undergoes to bring about successful pregnancy.
Aim: The early stages of acute renal failure are poorly diagnosed by current routine tests. We studied the correlation between cystatin C and creatinine in Type 2 diabetes patients. Introduction: The present study was carried out on 52 subjects with type 2 diabetes mellitus. All subjects were tested for various parameters like, serum cystatin C, serum creatinine, HbA1C, FBS, and, PP2BS. Analysis of Glomerular filtration rate was done using national kidney foundation formula. To analyze data Excel is used for SD value and Social Science Statistics for P value. Method: ScyC levels increased significantly in type 2 diabetes patients (p<0.001) as compare to SCre level. A positive correlation was present between ScyC and SCr (r=0.309, p<0.005). Both SCysC (r=-0.184) and SCr (r=-0.309) had adverse correlation with eGFR (p<0.005).Result: Serum cystatin C can be recognised as an immediate marker to detect nephropathy and renal dysfunction in diabetic patients than serum creatinine.Furthermore, this study needs to be conducted with a largest population to confirm this.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.