The formation of upper Paleozoic (Viséan to Sakmarian-Artinskian) Euramerican cyclothems, which resulted from base-level fluctuations of up to 100 m, commonly are attributed to large-scale waxing and waning of Gondwanan glaciers. However, evaluation of the geographic and chronostratigraphic distribution of Gondwana deposits reveals that glaciation was not the primary cause of base-level changes of that magnitude.Gondwana strata contain three non-overlapping glacial successions. Glacial I (Frasnian to possibly Tournaisian) and Glacial II (Namurian to lowermost Westphalian) rocks were deposited by alpine glaciers. Water sequestered by these glaciers was insufficient to account for the base-level changes. In contrast, Upper Carboniferous (Stephanian) to Lower Permian (Sakmarian-Artinskian) Glacial III rocks were widespread and indicate deposition by ice sheets that may have covered a total area of between 17.9 and 22.6 × 10 6 km 2 . Complete ablation of a single ice sheet of this size would produce eustatic changes of ~100 m. However, multiple ice sheets were likely present, which would have resulted in considerably smaller fluctuations in sea level during Glacial III deposition.The argument that Glacial I and II deposits were originally comparable in extent to those of Glacial III, but were eroded during the advance of Glacial III ice-sheets, is untenable. Weathered granite profiles on the pre-Glacial III unconformity occur scattered over a 1200-km length of the central Transantarctic Mountains. The profiles indicate prolonged subaerial exposure and, thus, an absence of ice cover. These and non-glacial successions in Gondwana constrain the size of ice sheets before Glacial III deposition and imply that glaciation prior to Glacial Episode III was not the primary cause of base-level changes linked to upper Paleozoic Euramerican cyclothems.