Ethyl 1‐fluoromethyl‐5‐(4,6‐dimethoxypyrimidin‐2‐ylcarbamoylsulfamoyl)pyrazole‐4‐carboxylate 1b, a new fluoromethyl analogue of the herbicide pyrazosulfuron‐ethyl la, was prepared from ethyl 1‐fluoromethylpyrazole‐4‐carboxylate 4b. The difluoromethyl and trifluoromethyl analogues 1c,d were also synthesized from ethyl pyrazole‐4‐carboxylate 2 via difluorocarbene reaction.
This review introduces the synthesis of various pyrazoles reported by us and some other research groups during 1989–1998. Some of papers in this review deal with the development of potent pyrazoles or with the synthesis of potential pyrazoles aiming at agrochemicals and/or drugs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.