Kawasaki disease (KD) is a multi-system disorder of unknown origin [4]. Although inflammatory changes in the pancreas have been reported in KD [1, 6], there have been few reports of clinical pancreatitis [2,3,5].A boy (aged 1 year and 8 months) was admitted to our hospital as having KD. Five days before admission, he was diagnosed with an influenza A infection and was prescribed oseltamivir for 5 days. Slightly increased levels of serum amylase (193 IU/; reference range 80-170 IU/l) with predominant pancreatic amylase isozyme (pancreas 90% versus salivary gland 10%; reference range 21%-65% versus 35%-79%), pancreas secretory trypsin inhibitor (138.6 ng/ml; reference range 4.2-12.2 ng/ml), elastase 1 (525 ng/dl; reference range 100-400 ng/dl), lipase (89 IU/l; reference range 11-53 IU/l), and pancreatic phospholipase A 2 (861 ng/dl; reference range 130-400 ng/dl) were noted with swelling of the pancreas. As he exhibited no symptoms suggestive of pancreatitis, he was not treated for severe pancreatitis and he received intravenous gamma globulin therapy (2 g/kg per day). He did not show any symptoms of acute pancreatitis during his stay and was discharged without complications.We retrospectively investigated cases of KD with increased levels of serum amylase on admission (>170 IU/l). We identified 12 cases with increased serum amylase levels among 138 KD patients (age range 1 month to 10 years and 5 months) (Table 1). Isozyme
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