This paper reports a method for rapid prototyping of cell tissues, which is based on a system that extrudes, aspirates and refills a mixture of cells and thermoreversible hydrogel as a scaffold. In the extruding mode, a cell-mixed scaffold solution in the sol state is extruded from a cooled micronozzle into a temperature-controlled substrate, which keeps the scaffold in the gel state. In the aspiration mode, the opposite process is performed by Bernoulli suction. In the refilling mode, the solution is extruded into a groove created in the aspiration mode. The minimum width of extruded hydrogel pattern is 114 ± 15 µm by employing a nozzle of diameter 100 µm, and that of aspirated groove was 355 ± 10 µm using a 500 µm-diameter nozzle. Gum arabic is mixed with the scaffold solution to avoid peeling-off of the gel pattern from the substrate. Patterning of Sf-9 cell tissue is demonstrated, and the stability of the patterned cell is investigated. This system offers a procedure for rapid prototyping and local modification of cell scaffolds for tissue engineering.
This paper reports an experimental demonstration of moiré metalens which shows wide focal length tunability from negative to positive by mutual angle rotation at the wavelength of 900 nm. The moiré metalens was developed using high index contrast transmitarray meta-atoms made of amorphous silicon octagonal pillars, which is designed to have polarization insensitivity and full 2π phase coverage. The fabricated moiré metalens showed focal length tunability at the ranges between ±1.73 – ±5 mm, which corresponds to the optical power ranges between ±578 – ±200 m−1 at the mutual rotation between ±90 degrees.
Metasurface lenses (metalenses) offer an ultrathin and simple optical system with dynamic functions that include focal length tuning. In this study, a rotational varifocal (i.e., moiré) metalens based on octagonal single-crystal silicon pillars was designed and fabricated to realize a high transmittance, whole 2π phase coverage, and polarization insensitivity for visible wavelengths. The moiré metalens consists of a pair of cascaded metasurface-based phase lattices and the focal length can be adjusted from negative to positive by mutual rotation. The fabricated moiré metalens demonstrated a focal length that can be tuned from −36 mm to −2 mm and from 2 to 12 mm by mutual rotation from −90° to 90°, and the experimental measurements agreed well with theoretical values at the design wavelength of 633 nm. Imaging was demonstrated at three distinct wavelengths of 633, 532, and 440 nm.
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