Electrical heat sources implanted in the abdominal cavities of sheep were heated to give initial temperatures of 42 degrees and 45 degrees C at the surfaces of the heaters. During 18 days of constant heating, a vascularized connective-tissue envelope encapsulated the heat sources, and the temperatures at the surfaces of the heaters declined 0.8 degrees and 1.8 degrees C, respectively. The degree of vascularization and the magnitude of the decrease in the surface temperature appeared to be related to the proximity of the tissue's initial temperature to 45 degrees C, a temperature ordinarily considered detrimental to cell structure. The vascularization thus appears to be adaptive.
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