Amantadine (or 1-adamantanamine) hydrochloride, a compound reported to be active against influenza viruses and Sendai virus, inhibited the growth of rubella virus in tissue culture. The antiviral activity appears at an early phase of the infection and is not due to direct inactivation of the virus.
Advances in wearable technologies provide the opportunity to monitor many physiological variables continuously. Stress detection has gained increased attention in recent years, mainly because early stress detection can help individuals better manage health to minimize the negative impacts of long-term stress exposure. This paper provides a unique stress detection dataset created in a natural working environment in a hospital. This dataset is a collection of biometric data of nurses during the COVID-19 outbreak. Studying stress in a work environment is complex due to many social, cultural, and psychological factors in dealing with stressful conditions. Therefore, we captured both the physiological data and associated context pertaining to the stress events. We monitored specific physiological variables such as electrodermal activity, Heart Rate, and skin temperature of the nurse subjects. A periodic smartphone-administered survey also captured the contributing factors for the detected stress events. A database containing the signals, stress events, and survey responses is publicly available on Dryad.
The occurrence of animal viruses in the aerosol emissions of wastewater treatment facilities was evaluated by direct assay and by the use of coliforms and coliphages as indicator organisms. Coliforms and coliphages were compared and evaluated with regard to their suitability as indicators of airborne animal viral contamination from wastewater treatment facilities. Two plants, one with treatment by activated sludge and the other by trickling filtration, were studied. Field air sampling procedures used large-volume air samplers, with recirculation devices, and Andersen samplers. Airborne viruses were enumerated by a most probable number (MPN) procedure. Partially treated liquid sewage contained about 1.0x 102 pfu 1-~ of animal viruses assayed on Buffalo Green IVlonkey (BGM) cells, 3.6 x 105 and 5.0 x 105 pfu It of coliphages, depending upon the E. coli host strain used for assay, and 2.0 x 10 9 colonies 1-~ of coliform bacteria. No airborne animal viruses were recovered, airborne coliphage levels averaged 2.3 x 10-t and 3.0 x 10-t MPNm-3, coliforms from aerosol emissions were 2.1 x 102 colonies m-3. Ratios of coliphages to animal viruses indicate that wastewater treatment plants may be continuous sources of low level concentrations of animal virus aerosols. Evidence shows coliforms to be much less stable than coliphages in the airborne state. Coliphages may be a more acceptable indicator of airborne animal viral contamination than coliforms.
Abstract--Survival of calf rotavirus and reovirus under controlled laboratory conditions in microorganism-free, distilled and wastewater at 8 and 26°C was examined by periodic measurement of cytopathic effects (CPE) and indirect fluorescent antibody (IFA) assays. Five samples of both water-types were collected and inoculated with the two viruses. Three samples of each type of water were divided into two bottles, one per virus, for incubation at 8°C. Two samples were used at 26°C, one per trial. In the absence of light and shaking at 26°C, 7 13 days were required for a loss of 90~o infectivity for rotavirus and reovirus, while at 8°C, averages were 80 days for rotavirus and 260 days for reovirus. Virus infectivity remained for more than 30 days at 26°C and 400 days at 8°C. Rates of decline were 10-100 times greater at 26 than at 8°C, but at both temperatures, the MPN log10 rate of decline of infectivity was linear.
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