Summary.A new aerobic gram-positive non-sporeforming bacillus has been isolated from infected genital hair of patients with white piedra in association with Trichosporon beigelii. This species has been characterised morphologically, nutritionally, by DNA base composition, cell-wall analysis and cellular fatty-acid profile on the basis of 14 isolates. The G + C content of DNA is 63-05 mol Yo. Cell walls possess meso-diaminopimelic acid (Type IV) and the sugars glucose, galactose, xylose and ribose ; mycolic acids are not present. The species has a distinct colonial and microscopic morphology, is strongly proteolytic and produces methanethiol. These findings and the cellular fatty-acid profile are compatible with the genus Brevibacterium. A new species is proposed based on the following characters : colonial and microscopic growth and morphology ; conditions for rod-to-coccus cycle ; ribose utilisation ; and tellurite reduction. The type strain has been named Brevibacterium rncbrellneri E2cr (ATCC 49030). The strong proteolytic properties may be the mechanism of pathogenesis.
The Jarisch-Herxheimer reaction is a self-limited, febrile episode that may occur following antibiotic therapy for syphilis. We report four cases of a heretofore unrecognized vesicular variant of the Jarisch-Herxheimer reaction. It is important to distinguish this phenomenon from an allergic drug eruption.
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