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This study aimed to investigate the temporal changes in the anterior chamber depth (ACD) and refractive prediction error (RPE) of 6 and 7 mm diameter intraocular lenses (IOLs) after cataract surgery or phacovitrectomy with or without sulfur hexafluoride (SF6) gas. We reviewed 120 eyes (120 patients) and divided them into six groups: three groups of cataract surgery alone and phacovitrectomy (with or without SF6), which were further divided according to IOL diameter (6 and 7 mm) used. We examined the ACD and IOL position using a swept-source anterior segment optical coherence tomograph at 1 day, 1 week, and 1 month postoperatively; and the RPE at 1 month postoperatively. The ACD and IOL position at postoperative day 1 in the SF6 injection groups were significantly smaller than those in the other groups (p < 0.01). At 1 week, the ACD and IOL position of the 6 mm IOL SF6 injection group was smaller than those in the other groups (p < 0.01); thus, complications such as synechia or pupillary capture should be considered in the early postopera-tive period of phacovitrectomy with SF6, especially in the 6 mm IOL. The ACD, IOL position, and RPE at 1 month did not significantly differ among the groups, regardless of the IOL diameter or SF6. In the SF6 injection groups, the ACD and IOL position gradually deepened with less gas.

Purpose: Choroidal osteoma, which typically affects young women, is a benign intraocular tumor composed of mature bone within the choroid. Tumor decalcification and subfoveal choroidal neovascularization often lead to poor visual acuity although the etiology is unknown. Choriocapillaris characteristics in choroidal osteoma also are unknown. Methods: We report 4 cases of choroidal osteoma with decalcification in which the choriocapillaris could be imaged by optical coherence tomography angiography (OCTA). Results: OCTA showed that the choriocapillaris structure was maintained in the calcified portion, whereas a loss occurred in parts of the decalcified portion in all cases. Conclusions: OCTA may be useful for understanding the pathological states of choroidal osteoma.

Purpose To investigate the impact of the local alert levels regarding coronavirus disease 2019 (COVID-19) on the clinical patterns of rhegmatogenous retinal detachment (RRD) in Japan. Study design Retrospective, single-center, consecutive case series. Methods We compared two groups of RRD patients, a COVID-19 pandemic group and a control group. Based on the local alert levels in Nagano, five periods during the COVID-19 pandemic were further analyzed: epidemic 1 (state of emergency), inter-epidemic 1, epidemic 2 (second epidemic duration), inter-epidemic 2, and epidemic 3 (third epidemic duration). Patients’ characteristics, including symptoms’ duration before visiting our hospital, macula status, and retinal detachment (RD) recurrence rate in each period, were compared with those in a control group. Results There were 78 patients in the pandemic group and 208 in the control group. The pandemic group had a longer duration of symptoms than the control group (12.0 ± 13.5 days vs. 8.9 ± 14.7 days, P = 0.0045). During the epidemic 1 period, patients had a higher rate of macula-off RRD (71.4% vs. 48.6%) and RD recurrence (28.6% vs. 4.8%) than the control group. This period also demonstrated the highest rates compared to all other periods in the pandemic group. Conclusion During the COVID-19 pandemic, RRD patients significantly delayed visiting a surgical facility. They showed a higher rate of macula-off and recurrence compared to the control group during the state of emergency than during other periods of the COVID-19 pandemic, although the difference was not statistically significant due to the small sample size. Supplementary Information The online version contains supplementary material available at 10.1007/s10384-023-00980-1.

P atients with branch retinal vein occlusion (BRVO) show reduced perfusion density (PD) in the area affected by the vein occlusion on optical coherence tomography angiography (OCTA). Although PD positively correlates with retinal sensitivity (RS) in the affected area (Rachima et al. 2020), patients may have decreased PD with preserved visual acuity (VA) posttreatment. Therefore, we hypothesized that the condition of the unaffected side is more important for VA than the PD or RS of the affected side. We examined how the central foveal retinal thickness (CFT), RS and PD at four points in the central region affect VA.Patients with major BRVO who received ranibizumab 0.5 mg/0.05 ml (Lucentis kit for intravitreal injection, 10 mg/ml; Novartis, Basel, Switzerland) 1+ pro re nata regimen at Shinshu University Hospital during 2017-2018 were assessed at baseline, 6 and 12 months postinitial treatment. CFT (CIRRUS HD-OCT; Carl Zeiss Meditec, Inc., Jena, Germany), RS (Microperimeter MP-3; Nidek Co., Ltd.) in quadrants around the central 2°(affected and unaffected, temporal and nasal), PD of the whole retinal segmentation (OCTA PLEX Elite 9000; Carl Zeiss Meditec, Inc.) and VA were measured (Fig. 1A-D). The association between VA and each variable was evaluated. To minimize OCTA artefacts, an eye-tracking function was used. Baseline PD was 1 month postinjection (Hasegawa et al. 2019), and all images had a signal References

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