Osteoarthritis is the most commonly seen arthritis, where there are 30.8 million adults affected in 2015. Magnetic resonance imaging (MRI) plays a key role to provide direct visualization and quantitative measurement on knee cartilage to monitor the osteoarthritis progression. However, the visual quality of MRI data can be influenced by poor background luminance, complex human knee anatomy, and indistinctive tissue contrast. Typical histogram equalisation methods are proven to be irrelevant in processing the biomedical images due to their steep cumulative density function (CDF) mapping curve which could result in severe washout and distortion on subject details. In this paper, the prominent region of interest contrast enhancement method (PROICE) is proposed to separate the original histogram of a 16-bit biomedical image into two Gaussians that cover dark pixels region and bright pixels region respectively. After obtaining the mean of the brighter region, where our ROI – knee cartilage falls, the mean becomes a break point to process two Bezier transform curves separately. The Bezier curves are then combined to replace the typical CDF curve to equalize the original histogram. The enhanced image preserves knee feature as well as region of interest (ROI) mean brightness. The image enhancement performance tests show that PROICE has achieved the highest peak signal-to-noise ratio (PSNR=24.747±1.315dB), lowest absolute mean brightness error (AMBE=0.020±0.007) and notably structural similarity index (SSIM=0.935±0.019). In other words, PROICE has considerably outperformed the other approaches in terms of its noise reduction, perceived image quality, its precision and has shown great potential to visually assist physicians in their diagnosis and decision-making process.
The rapid use of ultraviolet light emitting diodes (UV-LEDs) in various disinfection applications is growing tremendously due to their advantages unachievable using UV lamps. In this study, a comparison of standard LED at 460 nm wavelength and UVA LED at 385 nm was conducted to determine their effectiveness in disinfection of frequently isolated pathogens in hospitals (Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli). Determination of disinfection efficiency was carried out by measuring inhibition zone. Effects of varied exposure time on the inactivation of pathogenic microorganisms was studied. The results demonstrated that LED does not have germicidal activities. The highest inactivation for UVA LED was achieved for Pseudomonas aeruginosa. Linear relationship was found between exposure time and log reduction. This study showed that UVA LEDs can effectively inactivate significantly higher number of microorganisms hence can be used in disinfection of various applications.
<span>The excellent quality of color fundus photograph is crucial for the ophthalmologist to process the correct diagnosis and for convolutional neural network (CNN) models to optimize output classification. As a result of main causes as acquire devises efficiency and experience of a physician most fundus photographs can have uneven illuminance, blur, and bad contrast, in addition to micro-features of retinal diseases, which need to force their contrast. Fundus photograph quality assessment method is proposed to find out the perfect enhanced color fundus Technique in fundoscopy photographs-based CNN model. Five photograph quality measurements, in addition to five CNN metrics, were used as standard in this study. In this research innovative approach combining photograph quality measurement and CNN metrics analysis is proposed to find out the best enhance method that is set for the multiclass CNN model. The contrast enhancement techniques are evaluated using 267 color fundus photographs divided into three retina diseases cases were downloaded from the open-source database “FIGSHARE”. The study outcome showed that the presented system (single-CNN) can determine well the contrast enhancement method, as well as the low-quality fundus photograph then it can boost CNN metrics to achieve superior.</span>
<div>The automatic retinal disease diagnosis by artificial intelligent is an interesting and challenging topic in the medical field. It requires an appropriate image enhancement technique and a sufficient training dataset for the specific retina conditions. The aim of this study was to design an automatic diagnosis convolutional neural network (CNN) model which does not require a large training dataset to specifically identify diabetic retinopathy symptoms, which are cotton wool, exudates spots and red lesionin colour fundus pictures. A novel framework comprised image enhancement method by using upgraded contrast limited adaptive histogram equalization (UCLAHE) filter and transferred pre-trained networks was developed to classify the retinal diseases regarding to the symptoms. The performance of the proposed framework was evaluated based on accuracy, sensitivity and specificity metrics. The collected results have proven the robustness of the proposed framework in offering good accuracy in retina diseases diagnosis. </div>
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