Preventing infections post-transplantation has been shown to greatly improve outcomes in KT patients. [1][2][3]5 The number of KTs performed has been rising gradually this decade. In 2019, 23 400 KTs were performed in the United States, which is 6300 more than the number of KTs recorded just 5 years ago. 6 As these numbers increase, care providers must be proactive in optimizing immunity against vaccine-preventable diseases since they are associated with high rates of morbidity and mortality post-transplantation. 7,8 Live attenuated vaccines, including the MMR vaccination, are not generally recommended in post-KT recipients since patients are on lifelong immunosuppression and are contraindicated. The AST Clinical Practice Guidelines advise that live virus vaccine serologic screening for MMR be conducted for all pre-KT candidates and MMR vaccinations be given if required as early as possible before KT procedure. 4
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