We used carbon and nitrogen isotopes to investigate changes in the diet of California condors from the Pleistocene to the recent. During the Pleistocene, condors from California fed on both terrestrial megafauna and marine mammals. Early accounts reported condors feeding on the carcasses of marine mammals, but by the late 1700s, condor diets had shifted predominantly to terrestrial animals, following the commercial harvesting of marine mammals and the development of cattle ranching on land. At present, dairy calves provided by humans significantly augment condor diet, constituting an artificial support of the current population. Reestablishing a marine mammal component in the condor diet may be an effective strategy for fostering viable condor populations independent of direct human subsidies.carbon isotopes ͉ nitrogen isotopes ͉ paleodiet D uring the Pleistocene, California condors (Gymnogyps californianus) ranged from the Pacific coast of North America across the southern U.S. to Florida and north to western New York (1, 2). Historical records show that by the 17th century, condors were restricted to the west coast of North America, from Baja California to British Columbia (3, 4). At present, small reintroduced populations live in California, Arizona, and Baja California. Paleontological evidence suggests that populations of these obligate scavengers were associated with the carcasses of large animals (1). After the late Pleistocene extinction of most large terrestrial mammals in North America (5), condors appear to have been restricted to the west coast, where stranded marine mammals offered the only remaining abundant source of large animal carcasses (1).There is little direct evidence that marine mammals were a significant component of condor diets, however, beyond scattered historical observations. In 1806, Lewis and Clark observed condors feeding on whales near the mouth of the Columbia River (6). Captain Clark wrote on February 16, 1806: ''This bird fly's very clumsily, nor do I know whether it ever seizes it's prey alive, but am induced to believe it does not. We have seen it feeding on the remains of the whale and other fish which have been thrown up by the waves on the sea coast. These I believe constitute their principal food, but I have no doubt but that they also feed on flesh.'' In 1855, Taylor found hundreds of condors feeding on sea lion carcasses on the California coast (7). He wrote: ''During the early part of the present month, large quantities of sea lions have been killed on the southern coast for the oil; the carcasses of these animals on the beach may be seen at times surrounded by hundreds of the Condors. A friend of ours informed us that he saw a few days ago, as many as three hundred of these creatures near such feeding ground, within a distance of a league.'' (7). In the 1860s, Cooper reported on condors feeding on seal and whale carcasses in California, although he never directly observed them doing so (8).To investigate changes in condor diets, we determined the stable carbon ( 12 C...

Large-scale

BioOne Complete (complete.BioOne.org) is a full-text database of 200 subscribed and open-access titles in the biological, ecological, and environmental sciences published by nonprofit societies, associations, museums, institutions, and presses.

Abstract. Although there is strong epidemiologic evidence linking Schistosoma haematobium infection with carcinoma of the bladder, the utility of cytologic screening for urinary tract cancer has not been critically evaluated in S. haematobium-endemic populations. The present cross-sectional study examined urine cytology findings among 1,014 residents (ages 1 to 91) of the S. haematobium-endemic Msambweni area of Coast Province, Kenya. Among 705 evaluable cytology specimens, prevalence of inflammation (39%), hyperkeratosis (30%), metaplasia (33%), and frank atypia (0.4%) was notably higher than in previously studied, non-endemic populations. Overall, S. haematobium infection was strongly associated with increased risk for cytologic abnormality (Ͼ 2.8-fold relative risk of metaplasia or hyperkeratosis; P Ͻ 0.001). Age-group analysis confirmed parallel increases in metaplasia and S. haematobium infection prevalence early in life (from age 1 to 15 for both boys and girls). However, above age 20, metaplasia prevalence persisted at 33-45% prevalence despite a decline in infection prevalence and intensity. Prevalence of advanced (moderate or severe) metaplasia showed two age-related peaks: the first at 10-14 years of age (at the time of peak infection), and the second among subjects Ն 60 years old. No cancers were detected in the study population either on cytology or on follow-up ultrasound examination. These data suggest an age-dependent progression of cellular abnormalities in the urinary epithelium that is associated with chronic S. haematobium infection, which becomes independent of concurrent infection intensity as subjects grow older. Implications for cancer screening are discussed.

We investigated threats to the California condor (Gymnogyps californianus), a flagship endangered species, using individual data on survival during a 20 year period of intensive recovery efforts. Over the two decades of reintroductions, condors in California had an estimated median survival time of 7.8 years suggesting that 50% of condors are expected to survive in the wild long enough to contribute to recruitment. In general, annual mortality rates exceeded levels necessary for a stable population; however, mortality declined, reaching levels needed for population stability, during the second decade of re-establishment. Intensive management practices, including utility pole aversion training and clinical interventions to prevent lead-related deaths likely contributed to the decrease in mortality rates. Utility line collision and/or electrocution was an important factor causing mortality over the two decades; though, this threat has largely been mitigated through management and targeted efforts in high-risk areas. In the past, wildfires were not considered a major threat to survival of freeflying condors. However, our analyses suggest that forest fires are significantly linked to the hazard of death, and increased wildfire activity in California highlights this population's vulnerability to catastrophic losses from forest fire. Lead poisoning, which was a major driver in the population's decline, was a leading cause of death accounting for the greatest adult mortality, and lead exposure remains the most significant threat. Recent lead ammunition reduction efforts in the condor range in California hold promise for improving the recovery potential for this population.