Dear Editor, A 38-year-old Japanese woman presented with a 3-week history of recurrent itchy erythema with scales and sterile pustules on the trunk (Fig. 1a,b). She had been diagnosed with systemic lupus erythematosus (SLE), which manifested with antinuclear antibody positivity (1:640 homogenous and speckled), a high anti-dsDNA antibody titer (>300 IU/mL), polyarthritis and pericarditis 5 years previously. This was controlled with prednisolone sodium succinate (5 mg). She had no history of psoriasis vulgaris. She reported that itchy erythema with scales and a few pustules had developed during her second

We report a case of drug‐induced hypersensitivity syndrome (DIHS) due to diaminodiphenyl sulfone (dapsone) complicated by acute respiratory failure. Erythema only expanded from his preexisting prurigo. The proportion of regulatory T cells in the skin was relatively low, and overall steroid reactivity was favorable.

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