. DISCLAIMER • Thi» book wm preoeicd at in account ol work tponured by an agency ol the United Slaloi Government. Neither the United Stale* Government nor any agency thereof, nor any ol their ernpluyeei, matatenv warranty, eaurra or Implied, or auumei any letial liability or retpaniiollllv tot the accuracy, cnmpleleneu, ot uwlulneu rjl any Information, apparatus, ptoduct, or proceu dlKloud, or reprnsnla that 111 u»» rwutd not Infringe privately owned rlghu. Reference herein to any tpeclllc commercial prtxhjcl, proceu, or nrvlco by trade name, tredemarlt, manufacturer, or otherwlw, doei not necmtarlly conllltute or Imply 111 endotiement, recommendation, or favoring by the United Slates Government or any agency thereol. 3 , where Q is the flow rate, ah is the difference in hydraulic head, C is a constant that depends on the flow geometry and fluid properties, and 2b is the fracture aperture. The validity of this law for flow in a closed fracture where the surfaces are in contact and the aperture is being decreased under stress has been investigated at room temperature using homogeneous samples of granite, basalt, and marble. Tension fractures were artificially induced and the labor atory setup used radial as well as straight flow geometries. Apertures ranged from 250 ym down to 4 ym, which was the minimum size that could be attained under a normal stress of 20 MPa. Preliminary Report on Geophysical and Mechanical Borehole Measurements at

Effects of capsaicin, a pungent principle of hot red pepper, were studied in experiments using male rats fed a diet containing 30% lard. Capsaicin was supplemented at 0.014% of the diet. The level of serum triglyceride was lower when capsaicin was present in the diet than when it was not. Levels of serum cholesterol and pre-beta-lipoprotein were not affected by the supplementation of capsaicin. The perirenal adipose tissue weight was lower when capsaicin was present in the diet than when it was not. Hepatic enzyme activities of glucose-6-phosphate dehydrogenase and adipose lipoprotein lipase were lower in rats fed the 30% lard diet than in those fed a nonpurified diet. Activities of these two enzymes were higher when capsaicin was added to the diet than when it was not. Hepatic acetyl-CoA carboxylase, beta-hydroxyacyl-CoA dehydrogenase, and adipose hormone-sensitive lipase activities were not affected by capsaicin feeding. Lipid absorption was not affected by the supplementation of capsaicin. The perirenal adipose tissue weight and serum triglyceride were decreased as the level of capsaicin in the diet increased up to 0.021%. These results suggest that capsaicin stimulates lipid mobilization from adipose tissue and lowers the perirenal adipose tissue weight and serum triglyceride concentration in lard-fed rats.

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