Nodules or cysts of the oral mucosa occurred with an incidence of 88.7 per cent in 541 Japanese newborn infants. No infant was over 8 days old. This incidence is higher than that reported in Caucasian and Negro newborns. It may be suggested that the frequency of visible nodules have a close relation to growth and development in the fetal life, because the cysts seen in newborns can be recognized histologically in most fetuses, as demonstrated in other papers. Although a variety of terminology for these nodules have been used, these oral cysts can be classified as follows: gingival cyst in the newborn (dental lamina cyst) and median palatal mucosal cyst (Epstein's pearl).
A storiform neurofibroma on the back of a 23‐year‐old male is reported. The tumor grew slowly and continuously and with no sign of malignancy. The tumor was completely excised with no sign of recurrence in over one and one‐half years of follow‐up. The characteristic mat‐like structure and the presence of melanin in the cytoplasm of the tumor cells suggest that the tumor is of the melanotic type.
A new human diploid fibroblast-like cell strain has been established from dermal tissue of a 2 months old female embryo. This cell strain showed diploid karyotype and has a finite life span of 95-100 generations. No spontaneous transformation was observed during the whole life span in vitro. This cell strain is susceptible to SV40 infection and can be transformed easily by it.
A case of malum perforans pedis caused by spinal canal stenosis with spondylolisthesis in a 76-year-old female is reported with a brief review of literature. In our case, orthopedic and neurological evaluations were indispensable for correct diagnosis and treatment of the condition.
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