Quantitative evaluation of liver function by use of gadoxetate disodium (Gd-EOB-DTPA)-enhanced MR Imaging.
Manuscript type: Original research
Advance in Knowledge:The liver function corresponding to the plasma disappearance rate of indocyanine green (ICG-PDR) can be estimated quantitatively (R = 0.87) from the signal intensities and the volumes of the liver and the spleen on gadoxetate disodium-enhanced MR images.
Implications for Patient Care:1. Our study results suggest that (Gd-EOB-DTPA)-enhanced MR imaging of the liver may improve the early detection and treatment of liver diseases by evaluating anatomic and functional information on the liver by one examination.2. Gadoxetate disodium-enhanced MR imaging of the liver may allow quantitative estimation of segmental liver function.
Summary statement:The liver function corresponding with ICG-PDR can be estimated quantitatively from the signal intensities and the volumes of the liver and spleen on gadoxetate disodium-enhanced MR images, which may improve the estimation of segmental liver reserve. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Conclusion: The liver function correlating with ICG-PDR can be estimated quantitatively from the signal intensities and the volumes of the liver and spleen on gadoxetate disodiumenhanced MR images, which may improve the estimation of segmental liver function.
Evaluation of intranodular blood supply was valuable in predicting the prognosis in borderline lesions, except when only arterial blood supply was evaluated.
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