We report a case of ossifying fibroma involving the paranasal sinuses, orbit, and anterior cranial fossa. Ossifying fibroma is a benign fibro-osseous tumor, rarely involving the anterior cranial base. The patient was admitted because of exophthalmos and diplopia. The lesion was totally removed surgically. Grossly, it had a thin osseous capsule. The microscopic examination showed mainly fibrous tissues and lamellar bone trabeculae rimmed by osteoblasts and myxomatous areas in some parts. The histopathological aspect of this entity is discussed with reference to the differential diagnosis from monostotic fibrous dysplasia.
A nonfamilial case of Turcot syndrome (glioma-polyposis syndrome) is described. A 16-year-old male with no siblings first developed a frontal astrocytoma, and was later found to have colonic polyposis with adenocarcinoma. The family history was negative for the syndrome, but his parents were first cousins.
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