The Engineering Profession is seen as a holistic discipline affecting many areas of everyday life. Even though practicing professionals would not dispute the statement, it is often hard to convey the idea to preuniversity students, as it appears overwhelming and presumptuous. Examples comprising of many different subjects such as bridges, airplanes, and computers, are used to reduce the anxiety. But, these examples are part of everyday life and thus fail to inspire a new generation ofengineers. To overcome this problem, the University of Manitoba Space Applications and Technology Society is using a student-designed nano-satellite, T-Sat, as a means to promote the profession and motivate a new generation by making space accessible to undergraduate and graduate students. This paper describes the outreach presentations and hands-on workshops organized through a satellite design competition that have reached more than 3,000 pre-university students, university students, and industry professionals between January 2011 and May 2012.
BackgroundAs part of normal skin flora, Corynebacterium striatum (CS) can be isolated in clinical specimens and dismissed as a contaminant or colonizer. However, this organism is an emerging multi-drug-resistant opportunistic pathogen that causes serious infections and demonstrates worrisome resistance to antimicrobials. CS has been implicated in both osteomyelitis (OM) and septic arthritis (including prosthetic joint infections (PJI)), for which aggressive source control and antibiotics are needed. Because there is no accepted treatment standard when CS is found, we performed a retrospective analysis of patients with CS isolated from orthopedic sites.MethodsWe retrospectively analyzed cultures in which CS was isolated from 2015 to 2017. We restricted this analysis to patients with orthopedic cultures, bone and PJI. Charts were reviewed for clinical and microbiological data. Duration of follow-up was calculated to the last follow-up visit in our system for the patient after treatment of the infection. “Targeted” treatment was defined as treatment based on antimicrobial susceptibilities of the CS.ResultsWe identified 20 cases of OM and 6 PJI with CS identified in culture. 17/26 (65%) were multi-drug resistant. CS was the only organism (monomicrobial) in 46% (12/26) of cultures (8/20 OM, 4/6 PJI). All monomicrobial OM and PJI received targeted treatment and were cured clinically at the last follow-up (average 201 days OM and 124 days PJI). Of 12 polymicrobial OM infections, all improved clinically by last follow-up; 75% (9/12) were treated with targeted treatment for CS and 25% (3/12) without targeted treatment. All polymicrobial PJI (2/2, 100%) improved without targeted treatment.ConclusionOur review suggests that CS can cause OM and PJI, with a high rate of drug resistance. Cure rates are excellent in monomicrobial infections when therapy is targeted to susceptibility. The role of targeted therapy for polymicrobial infections in which another more likely pathogen is found is not clear, particularly in the setting of effective surgical source control. Further prospective research is necessary to clarify the prevalence and factors associated with CS infections, and the importance of treatment of this organism in orthopedic infections.Disclosures All authors: No reported disclosures.
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