Eagle syndrome includes elicitation of pain on swallowing, turning the head, or extending the tongue. The syndrome is thought to be caused by irritation of the glossopharyngeal nerve, most commonly caused by its impingement against an elongated styloid process. We present a rare case of a granular cell tumor presenting as Eagle syndrome. Granular cell tumors orignate from Schwann cells and are most common in the subcutaneous tissue of the head, neck, and oral cavity, especially the tongue. A granular cell tumor is typically benign and solitary, rarely malignant. The differential diagnosis, diagnostic algorithm, and treatment are presented.
of variance (general linear model-univariate procedure) to test the null hypotheses about the effects of age, diet, and age-diet interaction effects on the dependent variables, ie, various skin parameters.Results: Both age and diet had significant effects on the epidermal component of the skin. Diet effect was seen in the dermal thickness (F9.26,P.005) with larger values in aging AL animals. Dermal adipose tissue showed pronounced effects of calorie restriction (F5.89,P.021). Elastic and collagen fibers manifested tri-phasic age effect in both nutritional groups with higher values in adult animals. There was no noticeable change in the percentage area of pilosebaceous units.
Conclusion:This model shows alterations of skin histomorphology with age, some of which can be modulated with caloric restriction.Significance: Microscopic studies are useful for investigating the effects of chemotherapeutic agents on the skin in suitable age-controlled laboratory animals. The use of CR animals may elucidate whether dietary control can modify the response to such therapies.
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