The aim of this study was to determine the therapeutic success of the medical treatment of canine pyometra with the antigestagen aglepristone and to document the recurrence rate in relation to the time interval after treatment with antigestagens. In 48 (92.8%) of the 52 treated bitches, healing could be achieved within the first 3 weeks after the treatment had been started. One bitch died as a result of renal insufficiency; in three bitches there was no emptying of the uterus, so ovariohysterectomy became necessary. In these three patients, ovarian and endometrial cysts were present. Forty-one bitches could be followed up for 3 months. Four animals developed a recurrence (9.8%). In three bitches ovarian cysts and cystic endometrial hyperlasia could be found intra operationem. The development of 37 bitches could be followed for at least 1 year. Seven animals developed a pyometra again (18.9%). Two received a repeated treatment with aglepristone and have been free from recurrence for over 12 months. In 37 animals data on the subsequent sex cycles are available. In 22 bitches next heat started at the expected time, in seven animals heat started too early. In eight bitches the period of anoestrus was prolonged. Five of the six bred bitches delivered at least one litter. The presented data show that treatment of pyometra by aglepristone results in a high healing rate. The recurrence rate can be minimized by the selection of bitches without ovarian cysts and cystic endometrial hyperplasia.
Ultrasonographic images were acquired of the mammary glands of 40 bitches with physiologically lactating (n = 20) or inflamed glands (n = 20). Echogenicity, structure, homogeneity, thickness, and distinguishability of each tissue layer were assessed. Additionally, overall echogenicity was noted. In the normal lactating gland, different tissues could be differentiated easily. The parenchyma was, without exception, separated from adjacent tissues and was visible as medium echogenic tissue with a coarse-grained structure. The tissue always had some echogenic lines and anechoic areas and was slightly heterogeneous. The loss of distinct layering of the tissue was characteristic of an inflamed mammary gland and inflamed regions had reduced echogenicity. Additionally in five bitches with mastitis, the ultrasound examination was repeated five times for documentation of the progress of the illness and associated changes, supplemented with a color Doppler sonogram to assess changes in blood vessel density. Information from the examinations carried out via B-mode did not allow treatment success to be predicted. Two bitches with reduced blood vessel density centrally had a poor outcome whereas three bitches with increased blood vessel density had a good outcome. Thus, Doppler sonography might be a useful tool to obtain information of the prognosis in acute canine mastitis.
Zusammenfassung:Gegenstand und Ziel: Klinische, sonographische und mikrobiologische Untersuchungen an inflammatorisch veränderten kaninen Mammakomplexen. Material und Methode: Bei 15 Hündinnen mit Mastitis wurden 21 entzündlich veränderte Mammakomplexe klinisch und sonographisch untersucht. Weiterhin erfolgte eine bakteriologische Untersuchung von Sekret aus diesen Drüsenkomplexen und die Bestimmung der Leukozytenzahl im Blut. Bei fünf Patienten wurde der Krankheitsverlauf über fünf Untersuchungstermine sonographisch verfolgt und um die farbdopplersonographische Ermittlung des Durchblutungsstatus ergänzt. Ergebnisse: Die klinischen Erhebungen zeigen, dass weder das Allgemeinbefinden noch die Leukozytenzahl oder der bakteriologische Befund der Sekretuntersuchung einen Rückschluss auf den weiteren Krankheitsverlauf erlauben. Als typische sonographische Veränderung entzündeter Mammakomplexe gelten der Verlust der Gewebeschichtung, eine verminderte Echogenität, das Vorhandensein von multiplen anechogenen und echogenen Arealen sowie ein verändertes Schallverhalten. Anahnd dieser Charakteristika lässt sich jedoch keine Aussage über den weiteren Krankheitsverlauf treffen. Die sonographische Darstellung von Gaseinschlüssen im Gewebe wirft die Frage nach der Beteiligung von Anaerobiern am Entzündungsprozess der Mamma auf. Der bakteriologische Nachweis von Anaerobiern soll Gegenstand weiterer Untersuchungen sein. Mit der Farbdopplersonographie gelang es, eine Minderdurchblutung des Gewebes bei Erstvorstellung mit der Entwicklung zu einer Mastitis gangraenosa in Verbindung zu bringen. Schlussfolgerung und klinische Relevanz: Die sonographische Untersuchung des Gesäuges ermöglicht eine differenzierte Diagnose der Mastitis, erlaubt die Beschreibung der Ausdehnung der inflammatorischen Prozesse und kann die klinische und bakteriologische Untersuchung ergänzen. Die Untersuchung gestaltet sich einfach und ist als nichtinvasives Verfahren ohne Probleme durchführbar.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.