Thinning of the skin and probably a reduction in capillaries in the dermal layer contribute to a reduction in the blood flow response to heat. People with diabetes, in particular, have reduced skin heat dissipation because of less resting blood flow and thinner skin than that seen in age-matched controls.
The protective mechanism of PIV is severely reduced in older populations and those with diabetes, especially in colder environments where skin blood flow is already diminished.
In subjects with diabetes who are generally overweight and have impaired circulation, hot packs should be used with caution because of the low blood flows at rest and occlusion of the circulation under the belt with body movement.
There appears to be considerable blood flow reserve in younger subjects to tolerate heat stress. In contrast, older subjects and those with diabetes reach a critical level after which additional heat does not cause in increase in blood flow.
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