Patients who perceive a greater handicap as a result of dizziness demonstrate greater functional impairment than patients who perceive less handicap from dizziness.

Objectives/Hypothesis: To assess the efficacy of physical therapy for patients with a diagnosis of migraine-related vestibulopathy (MRV) or vestibular dysfunction with a history of migraine headache. Study Design: Retrospective case series Methods: Thirty-nine patients were identified through a retrospective chart review, 14 with a diagnosis of MRV and 25 with migraine headache. The patients were treated with a custom-designed physical therapy exercise program for a mean of 4.9 visits over a mean duration of 4 months. Patients completed the Dizziness Handicap Inventory (DHI), the Activities-Specific Balance Confidence Scale (ABC), and the Dynamic Gait Index (DGI), reported the number of falls they had experienced in the past 4 weeks, and rated the severity of their dizziness on an analogue scale of 0 to 100 at initial evaluation and at discharge. Results: Significant differences were seen before and after therapy in each of the outcome measures used. The average decrease in DHI score was 12 points (P < .01). ABC scores increased an average of 14 points (P < .01). Subjects increased their DGI scores an average of 4 points (P < .01). The number of patients reporting more than one fall decreased by 78% at discharge. (P < .05). Baseline symptoms of dizziness decreased an average of 11 points (P < .05). Conclusions: Patients with MRV and migraine headache demonstrated improvement in physical performance measures and selfperceived abilities after vestibular physical therapy.

The synthesis and characterization of air stable Fe(II) coordination complexes with tetrazine and triazolo-tetrazine ligands and perchlorate counteranions have been achieved. Time-dependent density functional theory (TD-DFT) was used to model the structural, electrochemical, and optical properties of these materials. These compounds are secondary explosives that can be initiated with Nd:YAG laser light at lower energy thresholds than those of PETN. Furthermore, these Fe(II) tetrazine complexes have significantly lower sensitivity than PETN toward mechanical stimuli such as impact and friction. The lower threshold for laser initiation was achieved by altering the electronic properties of the ligand scaffold to tune the metal ligand charge transfer (MLCT) bands of these materials from the visible into the near-infrared region of the electromagnetic spectrum. Unprecedented decrease in both the laser initiation threshold and the mechanical sensitivity makes these materials the first explosives that are both safer to handle and easier to initiate than PETN with NIR lasers.

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Many patients with bilateral vestibular loss benefit from an individualized vestibular physical therapy exercise program based on improved physical function and reduced self-perceived levels of handicap.

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We describe a simplified system of laser-driven flyer plates for shock compression science and shock spectroscopy. We used commercially available one-box Nd:YAG lasers and beam homogenization solutions to create two launch systems, one based on a smaller (400 mJ) YAG laser and an inexpensive diffusive optic, and one based on a larger (2500 mJ) laser and a diffractive beam homogenizer. The flyer launch, flight, and impact processes were characterized by an 8 GHz fiberoptic photon Doppler velocimeter. We investigated effects of different substrates, adhesives, absorbers, ablative layers, and punching out disks from continuous foils versus fabricating individual foil disks, and found that a simple metal foil epoxied to a glass window was satisfactory in almost all cases. Our simplified system launched flyer plates with velocities up to 4.5 km s(-1) and kinetic energies up to 250 mJ that can drive sustained steady shocks for up to 25 ns. The factor that limits these velocities and energies is the laser fluence that can be transmitted through the glass substrate to the flyer surface without optical damage. Methods to increase this transmission are discussed. Reproducible flyer launches were demonstrated with velocity variations of 0.06% and impact time variations of 1 ns. The usefulness of this flyer plate system is demonstrated by Hugoniot equation of state measurements of a polymer film, emission spectroscopy of a dye embedded in the polymer, and impact initiation and emission spectroscopy of a reactive material consisting of nanoscopic fuel and oxidizer particles.

We studied the between-therapist reliability and the validity of four instruments in measuring lumbar spine curvature and pelvic tilt. The four instruments and their measurements were 1) a tape measure to measure the change in lumbar curvature during trunk flexion; 2) a gravity goniometer to measure pelvic angle and lumbar curvature during stance, trunk flexion, and trunk extension; 3) a parallelogram goniometer to measure lumbar curvature during stance, trunk flexion, and trunk extension; and 4) a standard goniometer to measure the angle between wooden pointers mounted perpendicularly to the spine to obtain pelvic angle and lumbar curvature during stance, trunk flexion, and trunk extension. We found no single instrument to be the most reliable or valid. Between-therapist reliability ranged from .64 to .93 (Pearson product-moment correlation) and from .60 to .92 (interclass correlation coefficient). The validities of the instruments compared with measurements from roentgenograms generally were low, ranging from -.13 to .76 (Pearson product-moment correlation) and -.73 to -.05 (interclass correlation coefficient).