There is nothing more that can be done" is a phrase that may occasionally cross the minds of oncology nurses. This paper reports on the actions of exemplary oncology nurses who were faced with such situations where their colleagues gave up or turned away. The research question, "What actions do exemplary clinical oncology nurses (RNs) undertake in patient-care situations where further nursing interventions seem futile?" prefaced data collection via a secure website where 14 Canadian clinical oncology registered nurses (RNs) provided narratives documenting their actions. Thematic analysis utilized QRS NVivo 10 software and hand coding. Four themes were generated from data analysis: advocacy, not giving up, genuine presence, and moral courage. Implications for practice and future research are provided. "T here is nothing more that can be done." Besides hearing that patients have cancer, hearing (or sensing) that 'there is nothing more' is perhaps the most devastating experience for patients (Doell, 2008). Perry (2006) indicates that exemplary oncology nurses always seek to do something more for patients when usual nursing interventions have been ineffective or when others fail to act. More research is needed to better understand specific nursing interventions that may further assist all oncology nurses in taking action (Perry, 2006). The purpose of this research is to describe the actions of exemplary clinical oncology RNs who, when faced with other nursing colleagues who gave up or turned away, take action. BACKGROUND LITERATURE A search of CINAHL, Pub Med, Google Scholar, ProQuest, Sage, MEDline, and Health Source Nursing Archives Edition databases using the search terms "exemplary nurses," "exemplary oncology nurses," "expert oncology nurses," "futility," and "when nothing more can be done" revealed themes such as compassion fatigue, advocacy in nursing, mentoring in nursing, nursing vigilance, 'good' nurse, good work, moral dilemma, and stress. There were no direct references to actions of oncology nurses in responding to seemingly hopeless or futile situations where it seemed there were no further nursing interventions that could improve the patient's well-being. The exception is a study by Perry (2005a) who noted that cancer patients' "fear of being abandoned, of being given up on, of being left alone to face pain, technical procedures, or even death is immense" and that exemplary oncology nurses know this and take action (p. 20). Dias, Chabner, Lynch and Penson (2003) agree that upon hearing (or sensing) that nothing more can be done to improve their situations, patients often feel abandoned. While the literature is emphatic that no patient should ever be told that "there is nothing more to offer," nursing interventions described in the literature in such situations relate primarily to further attempts at symptom management and emotional support repeating previously tried interventions (